TY - JOUR AU - KITAMURA, CHINAMI AU - SIMANJUNTAK, PARTOMUAN AU - KAWAZOE, KAZUYOSHI AU - MAEHARA, SHOJI AU - OHASHI, KOZUYOSHI AU - SHIBUYA, HIROTAKA PY - 2011/09/30 TI - Enantiomeric ratio of sesamin in the bark of Pentaspadon motleyi (Anacardiaceae) JF - JURNAL ILMU KEFARMASIAN INDONESIA; Vol 9 No 2 (2011): JIFI KW - N2 - The barks of Pentaspadon motleyi Hook. f. (Anacardiaceae) were collected from the Poso district in Central Sulawesi, Indonesia, in 1992 which it has been used traditionally as a remedy for malaria and tuberculosis in the local area. It was found that a mixture of (+)-sesamin (1) and (-)-sesamin (2) in a ratio of 100:86 were present together with lupeol in the bark of Pentaspadon motleyi. This was the first evidence of sesamin being isolated in almost equivalent amounts of (+)- and (-)-forms from a single plant species, and indicates that the biosynthetic pathway of sesamin in the plant is not enantioselective or fuzzy. UR - http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/294