TY - JOUR AU - HARTATI, SRI AU - RAHMAWATI, DEDE AU - WIRYOWIDAGDO, SUJASWADI PY - 2011 TI - Isolation and Identification of Bioactive Compound of Aceton Extract Garcinia lateriflora Blume Leaf JF - JURNAL ILMU KEFARMASIAN INDONESIA; Vol 9 No 2 (2011): JIFI KW - N2 - Preliminary studies have been carried out phytochemical test acetone leaf extract Garcinia lateriflora Blume., and toxicity test against shrimp larvae (Artemia salina Leach) and murine cell line P388. Isolates which showed the highest mortality are proceeded further for fractionation, isolation and purification. The structure identification of active campound carriedout by analyzing the spectrum of IR , GC-MS (Gas chromatography mass spectrometer) and proton nuclear magnetic resonance spectrometer (1H-NMR ) and (13C-NMR ). The results showed that the most active against the larval shrimp Artemia salina L. with LC50 value of 18.03 ug/mL is b-asaron, IC50 of test results on cell line murine P-388 is 47.0 ug/mL. This compound was isolated first time from the plant Garcinia lateriflora BL. UR - http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/300