TY - JOUR AU - Widyastuthi, Febriza Risti AU - Wardoyo, Eustachius Hagni AU - Juliantoni, Yohanes PY - 2020/10/28 TI - Formulation of Gel Handsanitizer Atsiri Oil from Lemongrass (Cymbopogon nardus) with Hydroxy Propyl Methyl Cellulose (HPMC) as Gelling Agent JF - JURNAL ILMU KEFARMASIAN INDONESIA; Vol 18 No 2 (2020): JIFIDO - 10.35814/jifi.v18i2.690 KW - N2 - Gel handsanitizer wich is sell in the market today is mostly alcohol-based. Repeated use as a handsanitizer can cause dryness and irritation skin. An option is, we can substitute an alcohol into lemongrass oil (Cymbopogon nardus). There are three steps of the test, a preliminary test of oil concentration, a test of the physical properties of the gel preparation and a modifi ed replication test. Based on the preliminary test, citronella essential oil can kill Escherichia coli bacteria at a concentration of 5% and reduce Staphylococus aureus at 10% of concentration. The test of spread for gel in the physical test is between 5.5-6 cm with pH 7-9 and the adhesion is 1 second.The modifi ed replica test showed a signifi cant decrease in the number of bacterial colonies at each concentration formula of the three test groups. This signifi cance indicates the inhibition of bacteria caused by the use of hand sanitizing gels. Based on the organoleptic test and antibacterial test of hand sanitizer gel a chosen concentration is 10%. This concenrtration was liked by the public and could inhibit bacterial growth. UR - http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/690