Synthesis and Antioxidant Test of 1,5-bis(3’-etoksi-4’- hidroksifenil)-1,4-pentadien-3-on (EHP) Compound
Abstract
Synthesis of 1,5-bis(3’-etoxy-4’-hydroxyphenyI)-1,4-pentadiene-3-on (EHP) by aldol
condensation method from ethyl Vanilin and acetone, using hydrochloride acid as a catalyst, has been
conducted. Identification of the EHP compound was done through interpretation of UV-Vis, FT-IR,
GC-MS and NMR data, The antioxidant activity of EHP (IC50 8.66 µg/mL) is higher than curcumin (IC50
11.44 µg/mL) as demonstrated by the DPPH method.
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