Synthesis and Antioxidant Test of 1,5-bis(3’-etoksi-4’- hidroksifenil)-1,4-pentadien-3-on (EHP) Compound

  • ESTI MUMPUNI UNIVERSITAS PANCASILA
  • ENJANG RUSNAWAN UNIVERSITAS PANCASILA
  • EVI SULASTRI UNIVERSITAS PANCASILA
  • INDRIANA PERMATASARI UNIVERSITAS PANCASILA

Abstract

Synthesis of 1,5-bis(3’-etoxy-4’-hydroxyphenyI)-1,4-pentadiene-3-on (EHP) by aldol


condensation method from ethyl Vanilin and acetone, using hydrochloride acid as a catalyst, has been


conducted. Identification of the EHP compound was done through interpretation of UV-Vis, FT-IR,


GC-MS and NMR data, The antioxidant activity of EHP (IC50 8.66 µg/mL) is higher than curcumin (IC50


11.44 µg/mL) as demonstrated by the DPPH method.

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Published
2010-09-30
How to Cite
MUMPUNI, ESTI et al. Synthesis and Antioxidant Test of 1,5-bis(3’-etoksi-4’- hidroksifenil)-1,4-pentadien-3-on (EHP) Compound. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 8, n. 2, p. 91-100, sep. 2010. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/336>. Date accessed: 09 may 2025.
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