Clinical Trial the Efficacy of Boiled Hypertension Herbs Compared with Steeped Hypertension Herbs

  • Agus Triyono Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawangmangu
  • Peristiwan Ridha Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Danang Ardianto Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
DOI: https://doi.org/10.35814/jifi.v16i1.425

Abstract

To search for scientific evidence the efficacy of herbal medicine, has conducted clinical trial the efficacy of  hypertension herbs compared with hydrochlorotiazide. Efficacy of clinical trials were conducted with the design open-label, randomized clinical trials and parallel design. It was involving 80 subjects who have met the inclusion and exclusion criteria. Subjects randomized study that is divided into two groups, a herbs group  and hydrochlorotiazide group. Subjects performed once a week to check the complaint history, the development of clinical symptoms, the possibility of side effects and diagnostic physical examination. Assessment score of quality of life by questionnaires Short Form 36 (SF-36) every four weeks. Results showed that administration of herbal medicine for 56 days hypertension, lower blood pressure (systolic and diastolikic) is equivalent to hydrochlorotiazide (HCT). Lowering blood pressure to normal (normotensive) 62.7% of the subjects. Eliminating the clinical symptoms of hypertension (dizziness / headache, stiff neck / whiny and myalgia) herbs group subjects at almost the same time with the  hidrochlorthiazide group. Raising the quality of life scores (SF-36) subjects herbs group equivalent to the increase in quality of life scores (SF-36)  hydrochlorotiazide group.

References

1. Ross C. Brownson, Patrick L. Remington, James R. Davis. High Blood Pressure in Chronic Disease Epidemiology and Control. Second Edition. American Public Health Assosiation; 2009. p 262-264

2. Badan Penelitian dan Pengembangan Kesehatan Depkes RI. Riset Kesehatan Dasar (RISKESDAS). Jakarta; 2013.

3. Guyton, A.C., dan Hall, J.E. Buku Ajar Fisiologi Kedokteran. Jakarta. EGC; 2007

4. Perhimpunan Hipertensi Indonesia (PERHI). Pedoman Penanganan Pasien Hipertensi. Jakarta; 2007

5. Yogiantoro M. Hipertensi Esensial dalam Buku Ajar Ilmu Penyakit Dalam Jilid II Edisi V. Jakarta: Internal Publishing; 2009

6. Palmer A., dan Williams B. Tekanan Darah Tinggi. Jakarta: Erlangga; 2007

7. Dalimartha, S. Tanaman Obat di Lingkungan Sekitar. Jakarta: Puspa Swara; 2005

8. Peraturan Menteri Kesehatan Republik Indonesia. Nomor: 003/MENKES/PER /I/ 2010 tentang Saintifikasi Jamu dalam Penelitian Berbasis Pelayanan
Kesehatan. Jakarta. 2010.

9. Badan Litbang Kesehatan. Laporan penelitian Observasi klinik 4 ramuan jamu. Jakarta. 2011

10. Rustiani E, Andrajati R, Arsyanti L. analisis penggunaan obat antihipertensi di poliklinik rawat jalan rumah sakit pmi bogor: perbandingan cost effectiveness dan kualitas hidup pasien. Jurnal Ilmu Kefarmasian Indonesia, Vol. 12, No. 2; 2014, hlm. 209-215.
Published
2018-04-27
How to Cite
TRIYONO, Agus; RIDHA, Peristiwan; ARDIANTO, Danang. Clinical Trial the Efficacy of Boiled Hypertension Herbs Compared with Steeped Hypertension Herbs. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 16, n. 1, p. 78-85, apr. 2018. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/425>. Date accessed: 05 nov. 2024. doi: https://doi.org/10.35814/jifi.v16i1.425.
Citation Formats
Issue
Vol 16 No 1 (2018): JIFI
Section
Articles
License

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.