Anti-Acne Activity of Turi Leaves (Sesbania grandiflora (L.) Poir.) against Propionibacterium acne

  • Alvi Kusuma Wardani Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Mataram
  • Anna Pradiningsih Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Mataram
  • Nurul Qiyaam Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Mataram
  • Shah Iqbal Ikraman Akbar Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Mataram
DOI: https://doi.org/10.35814/jifi.v20i2.1086

Abstract

Turi (Sesbania grandiflora (L.) Poir.) is a native Indonesian plant with many benefits. One of the benefits of Turi leaves is that they can be used as antibacterial agents. Turi leaves contain several compounds with antibacterial bioactivity including tannins, flavonoids, and saponins. This study aimed to examine the activity of Turi leaf extracts against Propionibacterium acne, a bacterium that causes acne. Antibacterial activity testing was performed using the good diffusion method with three replicates. The test groups were X1, X2, and X3, which had extract concentrations of 5%, 7.5%, and 10%, respectively. The positive control group was treated with clindamycin disks. The results of measurements of the diameter of the inhibition zone showed that the mean for groups X1, X2, and X3 were 19.67 mm, 22 mm, and 23.67 mm, respectively. The positive control group was 37 mm. Based on the classifi cation of bacterial growth inhibition responses, the results of the inhibition zone diameter after deducting the good diameter × 10 mm were classifi ed as less eff ective for group X1 and weak for groups X2 and X3. The positive control group was classifi ed as strong. This study concluded that the antiacne activity of Turi leaf extracts at a concentration of less than 10% was weak when compared to the positive control.

References

1. Kurniati NF, Garmana AN, Aziz N. Aktivitas antibakteri dan antijamur ekstrak etanol akar, bunga, dan daun turi (Sesbania grandiflora L. Poir). Acta Pharmaceutica Indonesia. 2017;42(1):1-8.

2. Iien H, Zulkifli L, Sedijani P. Aktivitas Antibakteri Ekstrak metanol daun turi (Sesbania grandiflora L.) terhadap pertumbuhan Klebsiella pneumoniae. Jurnal Biologi Tropis. 2020;20(2):219-26.

3. R atnah S , R ahim AR, Ha syim H. Aktivit as Antimikroba Ekstrak Daun Turi Putih (Sesbania grandiflora L.) terhadap pertumbuhan Candida albicans dan Staphylococcus aureus. Media Farmasi. 2018;14(1):17-21.

4. Asmara AP. Uji fitokimia senyawa metabolit sekunder dalam ekstrak metanol bunga turi merah (Sesbania grandiflora L. Pers). Al-Kimia. 2017:5(1):48–59. https://doi.org/10.24252/al-kimia.v5i1.2856

5. Nugraha SE, Suryadi Achmad, Erly Sitompul. Antibacterial activity of ethyl acetate fraction of passion fruit peel (Passiflora Edulis Sims) on Staphylococcus aureus and Escherichia coli. Indonesian Journal of Pharmaceutical and Clinical Research. 2019; 2(1):712. https://doi.org/10.32734/idjpcr.v2i1.972

6. Detha A, Datta FU. Skrining fitokimia minuman tradisional moke dan sopi sebagai kandidat antimikroba. Jurnal Kajian Veteriner. 2016;4:12–6.

7. McLaughlin J, Watterson S, Layton AM, Bjourson AJ, Barnard E, McDowell A. Propionibacterium acnes and acne vulgaris: new insights from the integration of population genetic, Multi-Omic, Biochemical and Host-Microbe Studies. Microorganisms. 2019;7(5):
1-28. doi: 10.3390/microorganisms7050128.

8. Pelen S, Wullur A, Citraningtyas G. Formulasi sediaan gel antijerawat minyak atsiri kulit. 2016;5(4):136-42.

9. Atika BND. Antifungal activity of pare leaf (Momordica charantia L.) methanol extract. Evolusi: Journal of Mathematics and Sciences. 2021;5(1):22–7.

10. Mahmudan FL, Atun S. Uji aktivitas antibakteri dari ekstrak etanol temukunci (Boesenbergia pandurata) terhadap bakteri Streptococcus mutans. Jurnal Penelitian Saintek. 2017;22(1):59-66.

11. Reji L, Tolar BB, Smith JM, Chavez FP, Francis CA. Depth distributions of nitrite reductase (nirK) gene variants reveal spatial dynamics of thaumarchaeal ecotype populations in coastal Monterey Bay. Environmental microbiology. 2019;21(11):4032-45.

12. Rohmah J. Perbandingan daya antioksidan ekstrak aseton daun dan batang turi putih (Sesbania grandiflora) dengan metode dpph (diphenilpycrylhydrazil) [Prosiding]. SNHRP-I Inovasi, Teknologi dan Pendidikan Guna Mewujudkan Indonesia Sejahtera di Era Industrialisasi 4.0. 2018;249-57.

13. Septiani G, Susanti S, Sucitra F. Effect of different extraction method on total flavonoid contents of Sansevieria trifasciata P. leaves extract. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy).2021;7(2):143–50. https://doi.org/10.22487/j24428744.2021.
v7.i2.15573

14. Zhang QW, Lin LG, Ye WC. Techniques for extraction and isolation of natural products: a comprehensive review. Chin Med. 2018;13:1-20. doi: 10.1186/s13020-018-0177-x.

15. Akbari S, Abdurahman NH, Yunus RM. Optimization of saponins, phenolics, and antioxidants extracted from fenugreek seeds using microwave-assisted extraction and response surface methodology as an optimizing tool. Comptes Rendus Chimie.
2019;22(11):714–27. https://doi.org/https://doi.org/10.1016/j.crci.2019.07.007

16. Senduk TW, Montolalu LADY, Dotulong V. The rendement of boiled water extract of mature leaves of mangrove Sonneratia alba. Jurnal Perikanan Dan Kelautan Tropis. 2020;11(1):9-15. https://doi.org/10.35800/jpkt.11.1.2020.28659

17. Sani RN, Fithri CN, Ria DA, Jaya MM. Analisis rendemen dan skrining fitokimia ekstrak etanol mikroalga laut Tetraselmis chuii. Jurnal Pangan dan Agroindustri. 2014:2(2):121-26

18. Nurhayati LS, Yahdiyani N, Hidayatulloh A. Perbandingan pengujian aktivitas antibakteri starter yogurt dengan metode difusi sumuran dan metode difusi cakram. Jurnal Teknologi Hasil Peternakan. 2020;1(2):41-6. https://doi.org/10.24198/jthp.v1i2.27537

19. Hasanuddin P, Salnus S. Uji Bioaktivitas minyak cengkeh (Syzygium aromaticum) antibacterial activity of clove oil (Syzygium aromaticum) in inhibiting the growth of Streptococcus mutans causing dental disease. Bioma: Jurnal Biologi Makassar. 2020;5(2):241–50.

20. Pratami DK, Indrawati T, Istikomah I, Farida S, Pujianto P, Sahlan M. Antifungal activity of microcapsule propolis from Tetragonula spp. to Candida albicans. Communications in Science and Technology. 2020;5(1):16-21.

21. Setyani W, Yakub J, Yandri O, Kawan VR, Haryanto TJ, Darmika IM. Phytochemical Investigation and Antibacterial activity ethanol extract of papaya seeds (Carica papaya L.) applicated for gel product. Jurnal Ilmu Kefarmasian Indonesia. 2020;18(1):96-100.
Published
2022-10-30
How to Cite
WARDANI, Alvi Kusuma et al. Anti-Acne Activity of Turi Leaves (Sesbania grandiflora (L.) Poir.) against Propionibacterium acne. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 20, n. 2, p. 169-174, oct. 2022. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1086>. Date accessed: 20 apr. 2024. doi: https://doi.org/10.35814/jifi.v20i2.1086.
Citation Formats
Issue
Vol 20 No 2 (2022): JIFI
Section
Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.