Antibiotic Prescribing Pattern in Patients with Diabetes Mellitus Complications in Panembahan Senopati Bantul Hospital

  • Eva Nurjanah Pharmacy Study Program, Faculty of Health Sciences, Universitas Alma Ata Yogyakarta, DIY Yogyakarta 55184, Indonesia
  • Daru Estiningsih Pharmacy Study Program, Faculty of Health Sciences, Universitas Alma Ata Yogyakarta, DIY Yogyakarta 55184, Indonesia
  • Nurul Kusumawardani Pharmacy Study Program, Faculty of Health Sciences, Universitas Alma Ata Yogyakarta, DIY Yogyakarta 55184, Indonesia
  • Ninisita Sri Hadi General Hospital (RSUP) Dr. Sardjito, DIY Yogyakarta 55281, Indonesia

Abstract

Diabetes Mellitus, one of the non-communicable diseases (NCDs), is the leading cause of death in addition to cardiovascular disease, cancer, and chronic respiratory disease. The Basic Health Research (Riskesdas) recorded that Yogyakarta experienced a prevalence increase of 97% in 2013-2018, the second-highest in Indonesia. Uncontrolled sugar levels cause deterioration of the immune system. This study aims to determine the pattern of prescribing antibiotics and the occurrence of comorbid complications, both infectious and non-infectious. This was a non-experimental descriptive study with a cross-sectional design. The data was collected from patient's medical records retrospectively from July to December 2019. Furthermore, 65 medical records were taken using a simple random sampling method. A descriptive statistical analysis was performed, and the results were presented as percentages. The percentage of infectious and non-infectious comorbid diabetes mellitus II in Panembahan Senopati Bantul Hospital was 22.2% and 77.8%, respectively. The prescribing pattern primarily used was ceftriaxone (23.5%). The antibiotic class mainly prescribed was cephalosporin (49%).

References

1. Kemenkes RI. Riset Kesehatan Dasar (RISKESDAS). Badan Penelitian dan Pengembangan Kesehatan, 2018;120.

2. Kshanti IAM, Wibudi A, Sibaani RP, Saraswati MR, Dwipayana IMP, Mahmudji HA, et al. Pedoman Pemantauan Glukosa Darah Mandiri. Perkumpulan Endokrinologi Indonesia, 2019;28.

3. Utami ER. Antibiotika, Resistensi, Dan Rasionalitas Terapi. Sainstis. 2012;1(4):191–8.

4. Gumilas NSA, Harini IM, Samodra P, Ernawati DA. Karakteristik Penderita Diabetes Melitus (Dm) Tipe 2 Di Purwokerto. J Kesehatan, 2018;1(2):14–5.

5. Ramadhan N, Marissa N. Karakteristik Penderita Diabetes Mellitus Tipe 2 Berdasarkan Kadar Hba1C Di Puskesmas Jayabaru Kota Banda Aceh. Sel. 2015;2(2).

6. Wahyuni S, Alkaff RN. Diabetes Melitus Pada Perempuan Usia Reproduksi Di Indonesia. J Kesehat Reproduksi [Internet]. 2013;3(1):46–51. Available from: https://media.neliti.com/media/publications/107315-ID-diabetes-mellitus-pada-perempuan-usia-re.pdf

7. Lee S hee, Lee J, Liu X, Bonk CJ, Magjuka RJ. A Review of Case-based learning Practices in an online MBA program: A program-level Case Study. Educational Technology Society. 2009;12(3):178–90.

8. Suastika K, Dwipayana P, Siswadi M, Tuty RA. Age is an Important Risk Factor for Type 2 Diabetes Mellitus and Cardiovascular Diseases. Glucose Toler. 2012;

9. Musyafirah D, Rismayanti, Ansar J. Faktor yang Berhubungan dengan Kejadian Komplikasi DM pada Penderita DM di RS Ibnu Sina, J Kesehatan Masyarakat, 2017;1–12.

10. Tessaro FHG, Ayala TS, Nolasco EL, Bella LM, Martins JO. Insulin Influences LPS-Induced TNF-α and IL-6 Release Through Distinct Pathways in Mouse Macrophages from Different Compartments. Cell Physiol Biochem. 2017;42(5):2093–104.

11. Berbudi A, Rahmadika N, Tjahjadi AI, Ruslami R., Type 2 Diabetes and its Impact on the Immune System. Current Diabetes Revews, 2019;16(5):442–9.

12. Hajma LPA. Evaluasi Penggunaan Antibiotik Pada Penderita Diabetes Melitus Tipe 2 Dengan Komplikasi Ulkus/Gangren Di Instalasi Rawat Inap RSUD Dr Moewardi Surakarta. Repos Univ Muhammadiyah Surakarta [Internet]. 2017;2–4. Available from: http://eprints.ums.ac.id/48887/9/NASKAH PUBLIKASI FIX.pdf

13. Humaida R., Strategy To Handle Resistance of Antibiotics. Lampung University. 2014;3:113.

14. McCarthy K, Avent M. Oral or intravenous antibiotics?, Australian Prescriber, 2020;43(2):45–8.

15. Wen H, Jung H, Li X., Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges. AAPS J. 2015;17(6):1327–40.

16. Varley AJ, Sule J, Absalom AR., Principles of antibiotic therapy. Continuing Education in Anaesthesia, Critcal Care and Pain. 2009;9(6):184–8.

17. Kavitha V, Mrudula Y, Latha MS, Dinesh R, Srinivas GAB. Study of Prescribing Pattern of Antibiotics in The Management of Various Infectious Diseases in Warangal Region. Indian Journal of Medical Research and Pharmaceutical Sciences, 2016;3(January):13–35.

18. Estiningsih D, Puspitasari I, Nuryastuti T. Identifikasi Infeksi Multidrug-Resistant Organisms (MDRO) Pada Pasien Yang Dirawat di Bangsal Neonatal Intensive Care Unit (NICU) RSUP DR. Soeradji Tirtonegoro Klaten. J Manajemen dan Pelayanan Farm (Journal Management and Pharmacy Pract [Internet]. 2016 Sep 30 [cited 2020 Aug 11];6(3):243–8. Available from: https://dev.jurnal.ugm.ac.id/jmpf/article/view/29417/17566

19. Kemenkes, Lampiran Peraturan Menteri Kesehatan Nomor 2406/Menkes/Per/XII/2011 Tentang Pedoman Umum Penggunaan Antibiotik. Permenkes RI. 2011;(874):35–8.
Published
2023-04-29
How to Cite
NURJANAH, Eva et al. Antibiotic Prescribing Pattern in Patients with Diabetes Mellitus Complications in Panembahan Senopati Bantul Hospital. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 21, n. 1, p. 91-95, apr. 2023. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1150>. Date accessed: 22 dec. 2024. doi: https://doi.org/10.35814/jifi.v21i1.1150.
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Articles