Formulasi Sediaan Pelembab Ekstrak Buah Melon Orange (Cucumis melo L. var. reticulatus) Dalam Bentuk Krim

  • Mellisa Laura Mintoro Fakultas Farmasi, Universitas Katolik Widya Mandala Surabaya
  • Farida Lanawati Darsono Fakultas Farmasi, Universitas Katolik Widya Mandala Surabaya
  • Sumi Wijaya Fakultas Farmasi, Universitas Katolik Widya Mandala Surabaya
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Abstrak

Faktor eksternal lingkungan seperti paparan sinar matahari yang ekstrim dapat menganggu keseimbangan kulit dan menyebabkan kulit menjadi kering. Oleh itu, dibutuhkan suatu produk perawatan kulit seperti pelembab. Pada penelitian ini, sediaan topikal pelembab ini dikombinasikan dengan bahan alam yakni buah melon orange (Cucumis melo L. var. reticulatus) untuk menambah nilai guna dari sediaan. Buah melon orange mengandung senyawa humektan sukrosa sekaligus senyawa antioksidan yang mampu menormalkan kondisi kulit kering. Metode ekstraksi terpilih adalah metode perasan. Konsentrasi ekstrak yang digunakan adalah 10% (F1), 20% (F2) dan 30% (F3). Penelitian ini bertujuan untuk mengetahui pengaruh peningkatan konsentrasi ekstrak melon orange terhadap mutu fisik, efektivitas daya melembabkan, daya antioksidan serta mengetahui formula sediaan krim pelembab terbaik. Evaluasi sediaan meliputi mutu fisik, efektivitas daya pelembab, dan aktivitas antioksidan sediaan. Aktivitas antioksidan diuji menggunakan metode DPPH. Hasil analisa statisitik menunjukkan bahwa peningkatan konsentrasi ekstrak melon orange berpengaruh signifikan terhadap mutu fisik : pH, viskositas, daya sebar, daya tercucikan air, daya lekat dan efektivitas daya pelembab. Peningkatan konsentrasi ekstrak menyebabkan peningkatan signifikan pada efektivitas daya pelembab sediaan yang mengandung senyawa pelembab sintetis. Formula terbaik yang memenuhi spesifikasi uji mutu fisik dan efektivitas serta memiliki nilai tambah khasiat antioksidan adalah F2 (konsentrasi ekstrak 20%).

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Diterbitkan
2022-10-31
##submission.howToCite##
MINTORO, Mellisa Laura; DARSONO, Farida Lanawati; WIJAYA, Sumi. Formulasi Sediaan Pelembab Ekstrak Buah Melon Orange (Cucumis melo L. var. reticulatus) Dalam Bentuk Krim. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 20, n. 2, p. 291-301, oct. 2022. ISSN 2614-6495. Tersedia pada: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1164>. Tanggal Akses: 10 aug. 2025 doi: https://doi.org/10.35814/jifi.v20i2.1164.
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