The Effect of The Concentration of Bangle Ethyl Acetate Fraction Toward SPF Value in Temugiring Extract Cream

  • Anisa Lailatusy Syarifah Akademi Farmasi Putra Indonesia Malang
  • Andini Andini Akademi Farmasi Putra Indonesia Malang
  • Haritsah Alfad Akademi Farmasi Putra Indonesia Malang
DOI: https://doi.org/10.35814/jifi.v20i1.1214

Abstract

The concentration of bangle (Zingiber cassumunar) ethyl acetate fraction added in the formulation of the temugiring (Curcuma heyneana) extract cream formulation must be determined precisely since it may affect the Sun Protection Factor (SPF) value. This research aims to determine the effect of concentration variations of bangle ethyl acetate fraction on the SPF value of the temugiring extract cream. In this research, temugiring extract and bangle extract were obtained by remaceration employing ethanol, while the bangle ethyl acetate fraction was obtained by fractionation using n-hexane, ethyl acetate, methanol, and water. The bangle ethyl acetate fraction obtained was formulated in cream formulations of temugiring extract formulas 1, 2, and 3 with variations in the concentration of bangle ethyl acetate fraction 2%; 3%; and 4%. Furthermore, the SPF value was conducted using the UV-Vis spectrophotometry method. The results show that bangle ethyl acetate fraction concentration variations produced different SPF values for each cream formula. The SPF value for formulas 1, 2, and 3 was 11.466; 12.122; and 17.266. One Way ANOVA test produced a p-value of 0.037. Thus, it can be concluded that the concentration of the bangle ethyl acetate fraction would affect the SPF value in the cream temugiring extract.

References

1. Damogalad V, Edy HJ, Supriati HS. Formulasi krim tabir surya ekstrak kulit nanas (Ananas comosus L Merr) dan uji in vitro nilai sun protecting factor (SPF). Pharmacon. 2013 May 1;2(2).

2. Rejeki S, Wahyuningsih SS. Formulasi gel tabir surya minyak nyamplung (Tamanu Oil) dan uji nilai SPF secara in vitro. Universitas Research Colloquim. 2015; 97-103.

3. Sopyan I, Gozali D, Tiassetiana S. Formulation of tomato extracts (Solanum lycopersicum L.) as a sunscreen lotion. National Journal of Physiology, Pharmacy and Pharmacology. 2018;8(3):453-8.

4. Subchan, P., Malik DA, Namason WT. Fotoproteksi. MDVI. 2011. 38(3): 141-8.

5. Munifah M, Sari WY, Yuliastuti D. Uji Aktivitas Sun Protecting Factor Lotion Ekstrak Etanol 70% Kulit Jeruk Nipis Citrus aurantifolia. Jurnal Farmasetis. 2021 Nov 28;10(2):151-6.

6. Kristianto, S., Jati Batoro, Sri Widyarti, and Sutiman Bambang Sumitro. Exploration and economic value of medicinal plants as traditional herbal ingredients in Bangselok, Madura, Indonesia. Proceding of the 5th NA International Conference on Industrial Engineering and Operations Management Detroit, Michigan, USA. August 10-14, 2020; 3895-902.

7. Syarifah AL, Rurini R, Hermin S. Characterization of the curcuminoids fingerprints profile in curcuma and zingiber genera by TLC-digital image analysis. J. Pure App. Chem. Res. 2019 Jun 12;8(2):147-61.

8. Kusumawati I, Kurniawan KO, Rullyansyah S, Prijo TA, Widyowati R, Ekowati J, Hestianah EP, Maat S, Matsunami K. Anti-aging properties of Curcuma heyneana Valeton & Zipj: A scientific approach to its use in Javanese tradition. Journal of ethnopharmacology. 2018 Oct 28;225:64-70.

9. Li M, Xue Bai, Yong-Peng Ma, et al. Cosmetic potentials of extract and compounds from Zingiber cassumunar Roxb. Rhizome. Industrial Crops&Products. 2019; 141: 1-7

10. Suksaeree J, Laksana C, Fameera M, et al. Zingiber cassumunar blended patches for skin application: Formulation, physicochemical properties, and in vitro studies, Asian Journal of Pharmaceutical Sciences. 2015; 10: 341-49

11. Souza J.F., F.P. Campos, G.R. Packer, Determinação da atividade fotoprotetora e antioxidante em emulsões contendo extrato de Malpighia glabra L. Acerola, Rev. Ciên. Fram. Básic Apl. 2013; 34 (1): 69–77.

12. Mansur MC, Leitão SG, Cerqueira-Coutinho C, Vermelho AB, Silva RS, Presgrave OA, Leitão ÁA, Leitão GG, Ricci-Júnior E, Santos EP. In vitro and in vivo evaluation of efficacy and safety of photoprotective formulations containing antioxidant extracts. Revista Brasileira de Farmacognosia. 2016 Mar;26:251-8.

13. Syarifah AL, Retnowati R. Characterization of Secondary Metabolites Profile of Flavonoid from Salam Leaves (Eugenia polyantha) Using TLC and UVSpectrophotometry. Pharmaceutical Sciences and Research. 2019;6(3):4.

14. Pratama G, Yanuarti R, Ilhamdy AF, Suhana MP. Formulation of sunscreen cream from Eucheuma cottonii and Kaempferia galanga (zingiberaceae). InIOP Conference Series: Earth and Environmental Science 2019 May 1 (Vol. 278, No. 1, p. 012062). IOP Publishing.

15. Noviardi H, Ratnasari D, Fermadianto M. Formulasi Sediaan Krim Tabir Surya dari Ekstrak Etanol Buah Bisbul (Diospyros blancoi). Jurnal Ilmu Kefarmasian Indonesia. 2019 Oct 29;17(2):262-71.

16. Dutra EA, Kedor-Hackmann ER, Santoro MI.
Published
2022-04-30
How to Cite
SYARIFAH, Anisa Lailatusy; ANDINI, Andini; ALFAD, Haritsah. The Effect of The Concentration of Bangle Ethyl Acetate Fraction Toward SPF Value in Temugiring Extract Cream. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 20, n. 1, p. 120-127, apr. 2022. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1214>. Date accessed: 21 nov. 2024. doi: https://doi.org/10.35814/jifi.v20i1.1214.
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Vol 20 No 1 (2022): JIFI
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