Herbal Medicine Used to Increase the Libido of Male Mice (Mus musculus): Tribulus terrestris and Panax ginseng

  • Aguslina Kirtishanti Departement of Clinical-Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, East Java, 60293, Indonesia
  • Devyani Diah Wulansari Departement of Clinical-Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, East Java, 60293, Indonesia
  • Dini Kesuma Departement of Chemistry Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, East Java, 60293, Indonesia
  • I Gusti Ayu Laksmi Dwi Putri Departement of Clinical-Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, East Java, 60293, Indonesia
  • Amirah Nabila Rahmadinar Departement of Clinical-Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, East Java, 60293, Indonesia

Abstract

Tribulus terrestris and Panax ginseng are two therapeutic plants that might increase libido. The aim of the study was to see the effects of herbal medicine containing Tribulus terrestris and Panax ginseng on increasing male mice libido. This study used mice divided into two sets of 7 and 14 days. Each group was divided into four parts: control (solvent), comparator (Vitan), and test 1 (herbal medicine). Parameters measured were mice sexual behaviour (introduction, climbing, coitus), sperm concentration, sperm motility, and testicular weight. Except for coitus behaviour, there were no significant changes between groups in the 7 days of treatment. There were significant differences in introduction and climbing behaviour between the control group and test 2 after 14 days of treatment, but not in other parameters. There were no significant variations in any parameters of the mice’s libido between 7 and 14 days of treatment with 1x dose of herbal medicine; however, with 2x doses, only introduction behaviour showed a significant difference. Based on the research results, it can be concluded that administering two doses of herbal medicine can increase the frequency of treatment for 14 days.

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Published
2023-10-19
How to Cite
KIRTISHANTI, Aguslina et al. Herbal Medicine Used to Increase the Libido of Male Mice (Mus musculus): Tribulus terrestris and Panax ginseng. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 21, n. 2, p. 279-285, oct. 2023. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1485>. Date accessed: 25 may 2024. doi: https://doi.org/10.35814/jifi.v21i2.1485.
Section
Articles