Ionic liquid-based ultrasound-assisted extraction: a novel insights of green extraction techniques for bioactive compounds from herbal plants

  • Fiq'rah Lestari Aziz, Ms. Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia
  • Donny Lukmanto Department of Advanced Vision Sciences, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan http://orcid.org/0000-0001-8050-3828
  • Raditya Iswandana Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia http://orcid.org/0000-0003-2637-3844
  • Abdul Mu'nim Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia http://orcid.org/0000-0002-6681-9196

Abstract

The ionic liquid-based ultrasound-assisted extraction (ILUAE) is a non-conventional environmentally friendly extraction method. ILUAE is considered as green chemistry since ILUAE utilize ionic liquids as solvents and ultrasound-assisted extraction to extract bioactive chemicals from herbal plants. The growing popularity of ILUAE as preferred extraction method in herbal medicine is not only due to its sustainable, eco-friendly characteristics but also its improvement in extraction efficiency while maintaining the quality of extracted products. Here, we discussed and reviewed ILUAE as preferred extraction method for herbal medicines. Through discussing ILUAE’s potential, advantage against traditional extraction technique, and summarized the successful extraction of bioactive components from various herbal plants using ILUAE, we hope to showcase the technology's efficiency, selectivity, and sustainability. Finally, we discussed current limitations and future challenge for ILUAE and potential ways to address these challenges.

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Published
2024-04-30
How to Cite
AZIZ, Fiq'rah Lestari et al. Ionic liquid-based ultrasound-assisted extraction: a novel insights of green extraction techniques for bioactive compounds from herbal plants. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 22, n. 1, apr. 2024. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1531>. Date accessed: 21 june 2024. doi: https://doi.org/10.35814/jifi.v22i1.1531.