Assessment on the antioxidant, photoprotective, and antimicrobial properties of Siraitia grosvenorii

  • Figo Figo Departement of Biology, Faculty of Health Sciences, Universitas Pelita Harapan, Tangerang, 15810, Indonesia
  • Tasya Mariska Candra Departement of Biology, Faculty of Health Sciences, Universitas Pelita Harapan, Tangerang, 15810, Indonesia
  • Jessica Novia Departement of Pharmacy, Faculty of Health Sciences, Universitas Pelita Harapan, Tangerang, 15810, Indonesia
  • Marcelia Sugata Departement of Biology, Faculty of Health Sciences, Universitas Pelita Harapan, Tangerang, 15810, Indonesia
DOI: https://doi.org/10.35814/jifi.v23i1.1588

Abstract

Exogenous antioxidants from plant-based sources, such as polyphenols, show potential in maintaining a balance of cellular oxidation in biological systems. Additionally, the rise of antimicrobial resistance and the harmful effects of UV radiation on skin necessitate the exploration of medicinal plants for drug development and photoprotective agents. This study specifically focused on Siraitia grosvenorii or Luo Han Guo, and aimed to assess its phenolic and flavonoid content, as well as its antioxidant, antimicrobial, and photoprotective properties. The study involved the preparation of Siraitia grosvenorii extracts from seeds and fruit skins, determination of total phenolic and flavonoid content using Folin-Ciocalteu reagent and AlCl3, evaluation of antioxidant activity using the DPPH method, and analysis of antimicrobial activity against Escherichia coli using turbidity assays. Photoprotective activity was examined by calculating the Sun Protection Factor (SPF) using a UV spectrophotometer and a normalized function. The results showed that fruit skin of Siraitia grosvenorii had a higher total phenolic content than the seed, and no significant difference in flavonoid content between seed and fruit skin extract. Additionally, Siraitia grosvenorii fruit skin and seed had low SPF value and DPPH reduction. Both fruit skin and seed showed highest antimicrobial activity at the concentration of 100 ppm. 

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Published
2025-04-28
How to Cite
FIGO, Figo et al. Assessment on the antioxidant, photoprotective, and antimicrobial properties of Siraitia grosvenorii. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 23, n. 1, p. 1-7, apr. 2025. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1588>. Date accessed: 28 apr. 2025. doi: https://doi.org/10.35814/jifi.v23i1.1588.
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