Biotechnology-based Therapy for Stroke Treatment: Review
Abstract
Stroke is a degenerative disease that can cause a decrease in the quality of life for its survivors. Currently, various therapeutic agents have been used to treat stroke, such as antifibrinolytic, antihypertensive, statin, and antiplatelet drugs that can be given when a stroke occurs or to prevent secondary stroke attacks. However, along with the development of biotechnology and biomedical science, there is currently a lot of exploration of new stroke therapeutic agent candidates by utilizing some new signaling routes involved in stroke pathophysiology and the development of therapeutic agents developed using biotechnology methods. These therapeutic agents differ from small molecule drugs, especially in terms of their mechanism of action and manufacturing methods. This article exhibits the use of biotechnology-based therapeutic agents for stroke, including tissue plasminogen activators, therapeutic peptides, microRNA, monoclonal antibodies, and stem cells. These therapeutic agents have not only been tested on test animals but have also begun to be tested in clinical studies or have obtained marketing approval for use in ischemic stroke patients.
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Published
2024-10-31
How to Cite
UTAMA, Hieronimus Adiyoga Nareswara et al.
Biotechnology-based Therapy for Stroke Treatment: Review.
JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 22, n. 2, p. 248-260, oct. 2024.
ISSN 2614-6495.
Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1613>. Date accessed: 21 nov. 2024.
doi: https://doi.org/10.35814/jifi.v22i2.1613.
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