Nilai LD50 dan LC50 Ekstrak Etanol Herba Ketumpangan Air (Peperomia pellucida (L.) Kunth)

  • INDAH DWIATMI DEWIJANTI LIPI
  • MARISSA ANGELINA LIPI
  • SRI HARTATI LIPI
  • BETTY ERNAWATI DEWI UNIVERSITAS INDONESIA
  • LIA MEILAWATI LIPI

Abstract

Ketumpangan air (Peperomia pellucida (L.) Kunth), an Indonesian wild plant, is commonly found in every Indonesian region with moist shady place. People usually consume ketumpangan air as a fresh vegetables. Empirically, ketumpangan air is consumed to treat fever, stomach disease, kidney disorders, drug abscesses, boils acne, headaches, pain in arthritic and rheumatic gout, or other external treatment. In this research, we tested the acute toxicity of ethanol extract from ketumpangan air using experimental animals mice DDY strain. We also tested the Brine Shrimp Lethality Test (BSLT) using Artemia salina Leach larva shrimp. The main aim of this reseach was to determine the LD50 and LC50 values of ethanol extract from Ketumpangan air. The results showed that the ethanol extract was categorized as ‘mild toxic’. The calculation of LD50 with Reed and Munich method showed that the LD50 value for male and female group was 15.13 g/ kg and 11.87 g/kg respectively. The BSLT result showed that the LC50 values of Ketumpangan air was 81.28 ppm.

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Published
2017-11-30
How to Cite
DEWIJANTI, INDAH DWIATMI et al. Nilai LD50 dan LC50 Ekstrak Etanol Herba Ketumpangan Air (Peperomia pellucida (L.) Kunth). JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 12, n. 2, p. 255-260, nov. 2017. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/162>. Date accessed: 25 feb. 2020.
Section
Articles