The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu

  • Devita Hardi Faculty of Pharmacy, Pancasila University, South Jakarta, 12640, Indonesia
  • Yusi Anggriani Faculty of Pharmacy, Pancasila University, South Jakarta, 12640, Indonesia
  • Fredrick Dermawan Purba Department of Psychology, Faculty of Psychology, Universitas Padjadjaran, Jatinangor, West Java, 45363, Indonesia

Abstract

Quality of life is an important aspect for patients with type 2 diabetes mellitus (T2DM). Pharmacist counseling is a non-pharmacological effort that can be provided to improve quality of life and control blood glucose levels. This study aimed to determine the effect of pharmacist-led therapeutic counseling for T2DM patients on improving their quality of life and reducing blood glucose levels. The study used a quasi-experimental nonequivalent control group design, with pretest and posttest assessments conducted before and after the intervention at RSUD Pasar Minggu, South Jakarta. A total of 194 T2DM patients participated in the study, with 97 patients in both the intervention and control groups. Quality of life was measured using the EQ-5D-5L and EQ-VAS questionnaires, along with fasting blood glucose levels. Measurements were taken three times: before the intervention, and one month and two months after the intervention. Paired data were analyzed using the Wilcoxon test, while unpaired data were analyzed using the Mann-Whitney test at a significance level of 0.05. Counseling significantly improved EQ-5D-5L scores (Δ=0.06; p<0.001) and EQ-VAS scores (Δ=6.40; p<0.001), as well as reduced fasting blood glucose levels (Δ=-12.10 mg/dL; p<0.001) in the intervention group after the intervention. The impact of counseling was particularly significant in the pain/discomfort and anxiety/depression domains. However, no significant correlation was found between quality of life and fasting blood glucose levels in this study (p>0.05). Pharmacist counseling conducted at RSUD Pasar Minggu had a positive and significant impact on improving the quality of life and treatment outcomes related to blood glucose reduction.

References

[1] N. H. Cho et al., “IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045.,” Diabetes Res Clin Pract, vol. 138, no. 1, pp. 271–281, 2018.

[2] Riset Kesehatan Dasar, Laporan Nasional Riskesdas 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan Riset, 2018.

[3] D. Setyorini et al., “Peningkatan Kualitas Hidup Lanjut Usia (Lansia) di Kampung Penumping RW 03 dengan Latihan Fisik,” Jurnal Universitas Ahmad Dahlan, vol. 1, no. 1, pp. 1–5, 2020.

[4] World Health Organization, WHOQOL: Measuring Quality of Life. Geneva: World Health Organization, 1997.

[5] M. J. Davies et al., “Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).,” Diabetes Care, vol. 41, no. 12, pp. 2669–2701, 2018.

[6] L. Vinet and A. Zhedanov, “A ‘missing’ family of classical orthogonal polynomials,” J Phys A Math Theor, vol. 44, no. 8, p. 85201, 2011.

[7] R. P. Nugraha, “Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Yang Mendapat Antidiabetika Oral Di Puskesmas Kaliwungu Kabupaten Kudus Dengan Menggunakan Kuesioner DQLCTQ,” in Skripsi, Semarang: Universitas Sultan Agung, 2021.

[8] H. E. Septiar and P. Utami, “Pengaruh Konseling Farmasis Terhadap Kualitas Hidup Dan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2 di Puskesmas Gedong Tengen Periode Maret-Mei 2014,” Jurnal Farmasi Sains dan Praktis, vol. 1, no. 1, pp. 29–34, 2015.

[9] F. I. Pratiwi and A. Widayati, “Pengaruh Intervensi Tenaga Kesehatan terhadap Kepatuhan Minum Obat pada Pasien Diabetes Mellitus Tipe 2 di Indonesia: Kajian Literatur,” Jurnal Sains Farmasi & Klinis, vol. 8, no. 2, p. 107, 2021.

[10] S. B. Tondok, E. Watu, and W. Wahyuni, “Validitas instrumen European Qualitiy of Life (EQ-5D-5L) Versi Indonesia untuk menilai kualitas hidup penderita tuberkulosis,” EJurnal Malahayati, vol. 15, no. 2, pp. 267–273, 2021.

[11] D. Puspatari and S. Saidah, “Article Review: Effect of Counseling on Quality of Life in Type-2 Diabetes Mellitus Patients,” Medical Sains : Jurnal Ilmiah Kefarmasian, vol. 8, no. 3, pp. 1053–1066, 2023.

[12] S. Syarifuddin, A. Nasution, A. Dalimunthe, and Khairunnisa, “Impact of Pharmacist Intervention on Improving the Quality of Life of Patients with Type 2 Diabetes Mellitus.,” Macedonian journal of medical sciences, vol. 7, no. 8, pp. 1401–1405, 2019.

[13] W. M. Maw et al., “The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus,” Asian J Pharm Sci, vol. 11, no. 1, pp. 93–94, 2016.

[14] W. P. Rahmat, “Pengaruh Konseling terhadap Kecemasan dan Kualitas Hidup Pasien Diabetes Melitus di Kecamatan Kebakkramat,” in Tesis, Surakarta: UNS, 2010.

[15] I. R. C. E. S. Caetano, L. M. Santiago, and M. Marques, “Impact of written information on control and adherence in type 2 diabetes.,” Rev Assoc Med Bras, vol. 64, no. 2, pp. 140–147, 2018.

[16] R. M. Sagala, W. Arozal, R. Sauriasari, and S. Keban, “Evaluasi Penerapan Booklet dan Edukasi Apoteker pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Mayapada Tangerang,” Pharmaceutical Sciences and Research, vol. 4, no. 2, pp. 102–110, 2017.

[17] A. H. Khan, M. Z. Iqbal, S. A. Syed Sulaiman, A. Ibrahim, N. S. Binti Yusoff Azmi, and M. S. Iqbal, “Effect of pharmacist-led intervention on predictors of diabetic neuropathy at two different hospitals of Malaysia,” J Pharm Pharmacogn Res, vol. 9, no. 2, pp. 153–164, 2021.

[18] M. Butt, A. Mhd Ali, M. M. Bakry, and N. Mustafa, “Impact of a pharmacist led diabetes mellitus intervention on HbA1c, medication adherence and quality of life: A randomised controlled study,” Saudi Pharmaceutical Journal, vol. 24, no. 1, pp. 40–48, 2016.

[19] D. M. Scott, S. T. Boyd, M. Stephan, S. C. Augustine, and T. P. Reardon, “Outcomes of pharmacist-managed diabetes care services in a community health center,” American Journal of Health-System Pharmacy, vol. 63, no. 21, pp. 2116–2122, 2006.

[20] J. N. Lee, “The Effects of Pharmacist Intervention on Depression Medication Adherence: A Systematic Review,” in Thesis, Florida: University of Florida, 2006.

[21] R. Malathy, M. Narmadha, S. Ramesh, J. M. Alvin, and B. N. Dinesh, “Effect of a diabetes counseling programme on knowledge, attitude and practice among diabetic patients in Erode district of South India.,” J Young Pharm, vol. 3, no. 1, pp. 65–72, 2011.

[22] S. Pousinho, M. Morgado, A. Falcão, and G. Alves, “Pharmacist Interventions in the Management of Type 2 Diabetes Mellitus: A Systematic Review of Randomized Controlled Trials.,” J Manag Care Spec Pharm, vol. 22, no. 5, pp. 493–515, 2016.

[23] T. H. Nguyen et al., “A randomized controlled trial of a pharmacist-led intervention to enhance knowledge of Vietnamese patients with type 2 diabetes mellitus,” International Journal of Pharmacy Practice, vol. 30, no. 5, pp. 449–456, 2022.

[24] Fajriansyah, A. Iskandarsyah, I. M. Puspitasari, and K. Lestari, “Impact of pharmacist counseling on health-related quality of life of patients with type 2 diabetes mellitus: a cluster randomized controlled study.,” J Diabetes Metab Disord, vol. 19, no. 2, pp. 675–682, 2020.

[24] E. T. A. Setyani, D. Anggraini, R. A. Aulia, and A. W. Mukti, “Article Review : Peranan Apoteker Dalam Pelayanan Kefarmasian Pada Pasien Diabetes Melitus (DM),” Jurnal Sains Farmasi, vol. 4, no. 2, pp. 93–106, 2023.

[26] P. C. Lim et al., “The impact of pharmacist interventions, follow-up frequency and default on glycemic control in Diabetes Medication Therapy Adherence Clinic program: a multicenter study in Malaysia.,” J Pharm Policy Pract, vol. 16, no. 1, p. 83, 2023.
Published
2025-04-30
How to Cite
HARDI, Devita; ANGGRIANI, Yusi; PURBA, Fredrick Dermawan. The role of pharmacist counseling for patient with type 2 diabetes mellitus and its impact on blood glucose control and quality of life at RSUD Pasar Minggu. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 23, n. 1, p. 174-182, apr. 2025. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1685>. Date accessed: 06 may 2025. doi: https://doi.org/10.35814/jifi.v23i1.1685.