Development of Papaya Latex, Papaya Extract (Carica papaya L.) and Yam Bean Tuber Extract (Pachyrrhizus erosus (L.) Urb.) for Skin Lightening Lotion Based on Tyrosinase Inhibition and Antioxidant Activities

  • LEONARDUS BROTO SUGENG KARDONO LEMBAGA ILMU PENGETAHUAN INDONESIA
  • LIANDHAJANI LIANDHAJANI UNIVERSITAS PANCASILA
  • NINA ARTANTI LEMBAGA ILMU PENGETAHUAN INDONESIA
  • YETI MULYATI ISKANDAR LEMBAGA ILMU PENGETAHUAN INDONESIA
  • SITI MASRURAH BROTO SUTARYO UNIVERSITAS PANCASILA

Abstract

Whitening or skin lightening products are well known as cosmetic. In this development, papaya latex (Carica papaya L.), papaya fruit extract and yam bean tuber extracts (Pachyrrhizus erosus (L.) Urb.) were combined for skin lightening body lotion formula. Antioxidant and tyrosinase inhibitory activities were evaluated in the starting materials and the products. Antioxidant activity evaluation was conducted using DPPH free radical scavenging activity method. Tyrosinase inhibitory evaluation was performed based on tyrosinase enzymatic inhibitory reaction to tyrosine as substrate. Papaya latex showed the highest antioxidant activity (32.01%), followed by yam bean tuber extract (27.04%) and papaya extract (26.09%). The tyrosinase inhibitory activities of papaya latex, papaya fruit extract and yam bean tuber extracts were 68.42 %, 36.80% and 52.63 % respectively, as compared to that of arbutin (100%). Based on product appearance, color, odor, pH and viscosity, the product were stable for 128 weeks. The expired date calculation on its antioxidant activity, however, the product was stable for 77 weeks. It is recommended that the product should be stored in non transparent bottle at low temperature or at about 25-28oC.

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Published
2013-09-30
How to Cite
KARDONO, LEONARDUS BROTO SUGENG et al. Development of Papaya Latex, Papaya Extract (Carica papaya L.) and Yam Bean Tuber Extract (Pachyrrhizus erosus (L.) Urb.) for Skin Lightening Lotion Based on Tyrosinase Inhibition and Antioxidant Activities. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 11, n. 2, p. 191-196, sep. 2013. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/215>. Date accessed: 23 dec. 2024.
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Vol 11 No 2 (2013): JIFI
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