Characterization of Soursop Seed (Annona muricata L.) Granul and Effectivity Test Against the Larva of Aedes aegypti L. as Biolarvicidal Candidate

  • SARAH ZAIDAN UNIVERSITAS PANCASILA
  • RATNA DJAMIL UNIVERSITAS PANCASILA
  • SUPRIYONO SUPRIYONO INSTITUT PERTANIAN BOGOR
  • SITI Nuraini UNIVERSITAS PANCASILA

Abstract

A. aegypti mosquito is a vector of virus caused dengue fever. The effort to control A. aegypti vector has been done so many times, including chemical, physical and biological method. A biological control against this vector can be performed by utilizing soursop seeds which are known to have larvicidal effect against the larva. Previously, it has been proven that the extract of soursop seed demonstrated larvicidal activity against A. aegypti. In this research, the extraction of soursop seed has been carried out by kinetic maceration with the solvent 70% of ethanol. Furthermore, the wet granulation of the obtained extract was used for the preparation of granules which were then tested its larvicidal activity against A. aegypti. Based on the activity test against the larva of Aedes aegypti, the granules showed LC50 values of 295.434 ppm smaller than temephos as a positive control that has larvicidal activity of 1 ppm cause 100% mortality A. aegypti.

References

1. Kaihena M, Vika L, Maria N. Efektivitas ekstrak etanol daun sirih (Piper betle L) terhadap mortalitas larva nyamuk Anopheles sp dan Culex. Molluca medica. ISSN: 1979-6358.
2. Susanti P.D, Danang B, Dini S, Susilawati. Penggunaan ekstrak kulit kayu gemor (Nothaphoebe coriacea K.) sebagai larvasida hayati terhadap tingkat mortalitas 3. Jentik nyamuk Aedes aegypti serta dampaknya pada kualitas air hujan. ISSN 1978-8096. 2013.9:117– 22.
3. Hadi, Upik K. Penyakit tular vektor: demam berdarah dengue. Bogor: Fakultas Kedokteran Hewan IPB; 2005.
4. World Health Organization. Dengue: Guidelines for diagnosis, treatment, prevention and control, new edition. Swiss. 2010.5.
5. Palgunadi BU, Asih R. Aedes aegypti sebagai vektor penyakit demam berdarah dengue. Surabaya: Universitas Wijaya Kusuma. 2011.
6. Rosmayanti, Kiki. Uji efektivitas ekstrak biji sirsak (Annona muricata L ) sebagai larvasida pada larva Aedes aegypti Instar III/IV [skripsi]. Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Syarif Hidayatullah. 2014: 1-3, 16-7, 37-40.
7. Mulyawati A.P, Hayati E.K, Nashihuddin A, Tukimin. Uji efektivitas dan identifikassi senyawa ekstrak biji sirsak (Annona muricata Linn.) yang besifat bioaktif insektisida nabati terhadap hama thrips. Alchemy. 2010.2(1):104-1575.
8. Wardhana A.H, Amir H, Muharsini S, dan Yuningsih, Veteriner BP. Uji keefektifan biji sirsak (Annona muricata) dan akar tuba (Derris edliptica) terhadap larva Chrysomya bezziana secara in vitro. 2006; 1013-7.
9. Departemen Pertanian Indonesia. Metode standar pengujian efikasi pestisida rumah tangga dan pengendalian vektor. Direktorat Pupuk dan Pestisida dan Direktorat Jenderal Prasarana dan Sarana Pertanian Kementrian Pertanian. 2012:20-3.
10. Farnsworth NR. Biological and phytochemical screening of plants. Journal of pharmaceutical Sci. 1966.55(3).
11. Riswanto S. Uji efektivitas pestisida nabati terhadap hama Spodoptera litura (Lepidoptera: Noctuidae) pada tanaman tembakau (Nicotiana tabaccum L.). Medan: Universitas Sumatera Utara. 2009:20-3.
12. Susilowati D, Rahayu MP, Prastiwi R. Efek Penolak serangga (Insecct Repellent) dan larvasida ekstrak daun jeruk purut (Citrus hystrix D. C.) terhadap Aedes aegypti. Surakarta: Fakultas Farmasi, Universitas Setia Budi.
13. Nopitasari. Uji aktivitas ekstrak biji langsat (Lansium domesticum Cor.) sebagai larvasida Aedes aegypti. Universitas Tanjungpura. 2013: 12-4.
14. Zaidan S, Nuraini S. Efektivitas ekstrak dan sediaan granul biolarvasida dari biji sirsak (Annona muricata L.) terhadap larva nyamuk Aedes aegypti L.Prosiding SNIFA UNJANI, Cimahi-Bandung.2015. 15. Venugopala KN, Raquel MG, Kabange K, Bandar EA, Mahesh VA,Bharti O. Evaluation of halogenated coumarins for antimosquito properties. Hindawi Publishing Corporation The Scientific World Journal. 2014. Vol. 4.
Published
2016-09-30
How to Cite
ZAIDAN, SARAH et al. Characterization of Soursop Seed (Annona muricata L.) Granul and Effectivity Test Against the Larva of Aedes aegypti L. as Biolarvicidal Candidate. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 14, n. 2, p. 256-252, sep. 2016. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/229>. Date accessed: 05 nov. 2024.
Section
Articles