Antioxidant Activity of Prenylated Flavonoid Compound from Dichloromethane Extract of Artocarpus communis Leaves

  • PUSPA D.N. LOTULUNG LEMBAGA ILMU PENGETAHUAN INDONESIA
  • SOFA FAJRIAH LEMBAGA ILMU PENGETAHUAN INDONESIA
  • EUIS FILAILA LEMBAGA ILMU PENGETAHUAN INDONESIA

Abstract

This research investigated the antioxidant activity of prenylated flavonoid compound from the ichloromethane extract of Artocarpus communis leaves on 1,1-diphenyl-2-picryl hydrazyl free radicals scavenging assay. The dichoromethane extract of Artocarpus communis leaves was fractionated by column chromatography techniques on silica gel, and each fraction was assayed for its activity. The active compound, 1-(2,4-dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl] 1-propanone, showed moderate antioxidant activity with IC50 54.6 μg mL-1.

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Published
2011-09-30
How to Cite
LOTULUNG, PUSPA D.N.; FAJRIAH, SOFA; FILAILA, EUIS. Antioxidant Activity of Prenylated Flavonoid Compound from Dichloromethane Extract of Artocarpus communis Leaves. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 9, n. 2, p. 98-100, sep. 2011. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/293>. Date accessed: 21 nov. 2024.
Section
Articles