Antimicrobial Activity of Endophytic Fungi Kabatiella caulivora var. B Isolated from Alyxia reinwardtii BL

  • NOOR ERMA SUGIJANTO UNIVERSITAS AIRLANGGA
  • DIAN ANGGRAENY UNIVERSITAS AIRLANGGA
  • NOOR CHOLIES ZAINI UNIVERSITAS AIRLANGGA

Abstract

Endophytic fungi Kabatiella caulivora var B, have been isolated from Alyxia reinwardtii which was collected at Purwodadi Botanical Garden, Pasuruan, East Java. The objective of this present work is to asses the antimicrobial activity from extracts of the endophytic fungi Kabatiella caulivora var B against Bacillus subtilis, Escherichia coli, Salmonella thypi, Pseudomonas aeruginosa, Staphylocooccus aureus and Candida albicans. Disc diffusion method was conducted in this project with two concentration extracts (10 mg/disc and 5 mg/disc). The results showed that the methanol and ethyl acetate extracts of Kabatiella caulivora var B both have antimicrobial activity against all microbial tested, but the methanol extract showed negative activity against Staphylocooccus aureus and Candida albicans at concentration 5 mg. The discovery of endophytic fungi that produces bioactives metabolites has opened a promising new approach to obtain drugs on a commercial scale from microbes that grow inside plants.

References

1. Tejesvi MV, Nalini MS, Mahesh B, Prakash HS, Kini KR, Shetty HS, Subbiah V. New hopes from endophytic fungal secondary metabolites. Bol Soc Quim Méx., 2007. 1(1):19-26.

2. Strobel G and Daisy B. Bioprospecting for microbial endophytes and their natural products. Microbiology and Molecular Biology Rev. 2003. (67):491-502.

3. Tan RX and Zou WX. Endophytes a rich source of fungsional metabolites. Natural Prod Reports. 2001. (18):448-59.

4. StrobelGA. Endophytes as sources of bioactive products. Microbes and Infection. 2003. (5):535-44.

5. Steffan B. Inhaltsstoffe aus Pllanzen der Indonesischen Volksmedizin (Jamu): Isolierung, Identifizierung und Charakterisierung der antioxidativen Eigenschaften. Inaugural-Dissertation zue Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultat der Heinrich-Heine-Universitat Dusseldorf. [Dissertation], 2006. 195-6.

6. Sugijanto NE, DieselA, Ebel R, Indrayanto G, Cholies N. Chemical constituents of the endophytic fungus Lecythophora sp. isolated from Alyxia reinwardtii, Natural Product Communications. 2009. (4):1485-8.

7. Doughari J H. Research article antimicrobial activity of Tamarandus indica Linn. Tropical J Pharm Research. 2006. (5)2597-603

8. Sugijanto NE, Putra H, Pritayuni F, Albathaty N, Cholies N. Daya antimikroba ekstrak Lecythaphom sp., endofit yang diisolasi dari Alyxia reinwardtii, Berkala Penelitian Hayati. 2009. (15):3744

9. Raviraja NS. Fungal endophytes in five medicinal plant Species from Kudremukh Range. Western Ghats of India J Basic Microbiol. 2005. (45):230-5.

10. Aliero AA and Afolayan AJ. Antimicrobial activity of Solanum tomentosum. African J Biotechnology. 2006. (4):369-372.

11. Irfiani N. Studi profil kandungan metabolit jamur endoiit Kabatz‘ella caulivora (ALE 30 B) dari Alyxia reinwardtii BL secara KLT-Densitometri. [Skripsi]. Surabaya: Fakultas Farmasi Universitas Airlangga; 2005. 99-100.
Published
2011-04-30
How to Cite
SUGIJANTO, NOOR ERMA; ANGGRAENY, DIAN; ZAINI, NOOR CHOLIES. Antimicrobial Activity of Endophytic Fungi Kabatiella caulivora var. B Isolated from Alyxia reinwardtii BL. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 9, n. 1, p. 31-34, apr. 2011. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/320>. Date accessed: 27 dec. 2024.
Citation Formats
Issue
Vol 9 No 1 (2011): JIFI
Section
Articles
License

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.