Facial Wash Gel Product Development from Averrhoa bilimbi L. Fruits and Kalanchoe pinnata (Lam.) Per. Leaves Extract as An Antibacterial Causes of Acne

  • ANARISA BUDIATI UNIVERSITAS PANCASILA
  • ANNY VICTOR PURBA UNIVERSITAS PANCASILA
  • SHIRLY KUMALA UNIVERSITAS PANCASILA

Abstract

Averrhoa bilimbi L. fruits and Kalanchoe pinnata (Lam.) Per. leaves are useful as anti bacterial. The extracts containing the compound bufadienolides have the potential to be used as an anti bacterial. The purpose of this study to fi nd the best formula of the preparation facial wash gel with the active substance from the combination of extracts. Search methods extract concentration using the agar diff usion to obtain regional Diameter Inhibition (DDH) of each extract and the combinations. Research conducted with 3 forrmula containing extracts with diff erent concentrations. The results of the evaluation of the preparation at room temperature storage does not change the color, shape and scent. Retrieved best formula is the formula I containing a concentration of 0.7% resulting extract preparations light green and scented perfume. The results of the evaluation of the formula I at room temperature after 3 month storage include: high foam in hard water 17 mL, high foam in distilled water >25 mL, the specifi c gravity 1.0386 g/cm3, surface tension 19, 3627 dyne/cm, viscosity 853,33-1103,33 cPs, pseudoplastis fl ow properties, pH 5.16, anti bacterial test results using Diameter test Inhibitory Region shows constraints on Staphylococcus aureus by 5,0±0 mm.

References

1. Joshita D, editor. Buku pegangan ilmu pengetahuan kosmetik. Jakarta: PT. Gramedia Pustaka Utama; 2007:49-1, 149-5.

2. Djuanda A, Hamzah M, Aisah A. Ilmu penyakit kulit dan kelamin. Edisi V. Jakarta: Fakultas Kedokteran Universitas Indonesia Press; 2007:235.

3. Suryadi T. Kejadian dan faktor resiko acne vulgaris. Media Medika Indonesiana. 2008. 43(1):43-37.

4. Jawetz, Melnick, Adelberg. Mikrobiologi kedokteran. Edisi 20. Jakarta: Fakultas Kedokteran Universitas Indonesia press; 2005.290-1.

5. Cicilia S. Pembuatan sabun mandi gel alami dengan bahan aktif mikroalga Chlorella pyrenoidosa Beyerinck dan minyak atsiri Lavandula latifolia Chaix. Science and technology [skripsi]. Malang Universitas Ma Chung; 2012.2-1.

6. Tonny L, Lidya U. Uji efektifi tas antiseptik triclosan 1% terhadap Staphylococcus aureus, Escherechia coli, Enterococcus faecalis, dan Pseudomonas aeruginosa. Majalah Kedokteran Indonesia. 2007.5(6):172.

7. Hembing. Ensiklopedi milenium tumbuhan berkhasiat obat indonesia. Jilid 1. Jakarta: Prestasi Insan Indonesia; 2000.3-1.

8. Irwan. Pemanfaatan air belimbing wuluh sebagai alternatif untuk mengawetkan ikan dan daging, (O n lin e ), (h ttp:/ /ww w.s m u- n et. c om /m a in . php?act=ai&xkd=20), diakses 13 november 2007.

9. Dzihni KH. Formulasi krim antijerawat m/a dari ekstrak buah belimbing wuluh (Averrhoa bilimbi L.). Pharmacy science [skripsi]. Jakarta: Universitas Pancasila; 2010.40-1.

10. Magassouba F B, A Dialloa. Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine. J o Ethnopharmacology. 2007.114, 44-53.

11. Akinsulire O R, Aibinu I E, Adenipekun T, Adelowotan T, Odugbemi T. Invitro antimicrobial activity of crude extracts from plants Bryophyllum pinnatum and Kalanchoe crenata. African Journal of Traditional, Complementary and Alternatif Medicines. 2007.4(3):344-38.

12. Quazi M A, Tatiya, Molvi K, Sayyed N, Shaiks. The miracle plant (Kalanchoe pinnata): a phytochemical and pharmacological review. International Journal of Research in Ayurveda & Pharmacy. 2011.2(5):1478- 82.

13. Firdaus. Kartiningsih, Yantih N. Minimum inhibitory concentration (MIC) of powder ethanol extracts of Kalanchoe pinnata against Streptococcus mutans. ITB Journal of Science. 2010.5-1.

14. Okwu D E, Josiah. Evaluation of the chemical composition of two Nigerian medical plants. African Jornal of Biotechnology. 2006.5(4):357-61.
Published
2017-04-30
How to Cite
BUDIATI, ANARISA; PURBA, ANNY VICTOR; KUMALA, SHIRLY. Facial Wash Gel Product Development from Averrhoa bilimbi L. Fruits and Kalanchoe pinnata (Lam.) Per. Leaves Extract as An Antibacterial Causes of Acne. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 15, n. 1, p. 89-95, apr. 2017. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/461>. Date accessed: 26 july 2024.
Section
Articles