Combination extracts of Pandan Wangi Leaves (Pandanus amaryllifolius Roxb.) and Mengkudu Fruits (Morinda citrifolia) as Antifungal Against Fungi Causes Dandruff

  • AMBARWATI AMBARWATI UNIVERSITAS MUHAMMADIYAH SURAKARTA
  • TANTI AZIZAH SUJONO UNIVERSITAS MUHAMMADIYAH SURAKARTA
  • RETNO SINTOWATI UNIVERSITAS MUHAMMADIYAH SURAKARTA

Abstract

Dandruff is a scalp problem which causes itching and hair loss. It causes by microorganisms, especially fungi. Pandan Wangi (Pandanus amaryllifolius Roxb.) leaves and Noni (Morinda citrifolia) fruit are known have antifungal eff ect. The aim of this study was to determine the combination of 96% ethyl acetate extract of Pandan leaves and 96% ethanol extract of Noni fruit could inhibit fungal which isolated from dandruff . The fungi were isolated from dandruff sample on PDA (Potatoes Dextro Agar) and it was purifi ed. Based on the research, it was known the density of fungi was 9.2x108 colonies/ gram. Purifi ed from 17 types of fungal isolates in dandruff sample. The inhibition test of EPW:EP (1:1) showed that 82.4% fungal isolates inhibited, the diameter of inhibition zone ranging between 15-35 mm.There are three species of fungi: Aspergillus sp, Paecylomyces varotii, Candida sp (non albicans) and 1 isolate was yeast. The active compound in Pandan leaves extract: phenol (9.42% w/w) and fl avonoids (4.39% w/w), while in Noni fruit extract: alkaloids (1.97% w/w), phenol (12.50% w/w) and fl avonoids (8.61% w/w). It can be concluded that the combination of Pandan Wangi leaves and Noni fruit extract have potential used as anti-dandruff shampoo.

References

1. Potluri A, Shaheda ASK., Rallapally N, Durrivel S,Harish G. A review on herbs used in anti-dandruff shampoo and its evalution parameters. Indo American Journal of Pharmaceutical Research. 2013.3(4):3266- 78.

2. Chandrani D, Lubaina SZ, Soosamma M. A review of antifungal eff ect of plant extract vs chemical subtances against malassezia Spp. International Journal of Pharma and Bio Sciences. 2012.3(3):773-80.

3. Ariyani, Dewi SS, Haribi R. Daya hambat sampo anti ketombe terhadap pertumbuhan C. albicans penyebab ketombe. Jurnal Kesehatan. 2009.2(2):7-10.

4. Niharika A, Aquicio JM, Anand A. Antifungal properties of Neem (Azardirachta indica) leaves extract to treat hair dandruff . E-International Scientifi c Research Journal. 2010.2(3):244-52.

5. Gholib D. Pengujian penggunaan ekstrak etanol bawang putih (Allium sativum L.) terhadap kelinci yang diinfeksi dermatifi t Trichophyton mentagrophytes. Prosiding Seminar Nasional Teknologi Peternakan dan Veteriner. 2010:803-8.

6. Rai N, Jain AK, Abraham J. Formulation and evaluation of herbal antidandruff shampoo containing garlic loaded solid lipid nanoparticle. International Journal of Pharma Research & Review. 2013.2(10):12- 24.

7. Shinde PR, Tatiya AU, Surana SJ. Formulation development and evaluation of herbal antidandruff shampoo. International Journal of Research in Cosmetic Science. 2013.3(2):25-33.

8. Al Badi, Khan SA. Formulation, evaluation and comparison of the herbal shampoo with the commercial shampoo. Beni-Suef University Journal of Basic and Applied Sciences. 2014.3(4):301-5.

9. Fitri CR, Fitriningsih SP , Suwendar. Evaluasi potensi aktivitas antifungi ekstrak etanol daun pandan wangi (Pandanus amaryllifolius Roxb.) terhadap Candida albicans secara in vitro. Prosiding Farmasi Seminar Penelitian Civitas Akademika UNISBA. 2016.2(2):729 -36.

10. Srinivasahan V, Durairaj B. Antimicrobial activities of hydroethanolic extract of Morinda citrifolia fruit. Int Journal Curr Microbiol App Sci. 2014.3(9):26-33.

11. Ambarwati, Sujono TA, dan Sintowati R. Produksi sampo anti ketombe dari ekstrak daun pandan wangi dan biji mimba. Laporan Penelitian Hibah Bersaing Tahun I. 2015.

12. Sharma MC, Sharma S. Phytochemical screening of methanolic extract and antibacterial activity of Eclipta alba and Morinda citrifolia L. Middle-East Journal of Scienctifi c Research. 2010.6(5):445-49.

13. Kumar KT, Panda DS, Nanda UN, Kuntia S. Evaluation on antibacterial, antifungal and anthelmintic activity of Morinda citrifolia L. (noni). International Journal of PharmTech Research. 2010.2(2):1030-32.

14. Kakad SL, Pise SS, Dhembares AJ. Evaluation of phytochemical, antibacterial, antifungal activities of leaf extracts of Morinda citrifolia (Linn). Der Pharmacia Sinica. 2015.6(4):19-12.

15. Sunarni T, Prastiwi R, Mardiyono, Rinanto Y. Kombinasi ekstrak etanol buah mengkudu (Morinda citrifolia L.) dan daun pepaya ( Carica papaya L.) sebagai hepatoprotektif selama pengobatan tuberkulosis. Jurnal Ilmu Kefarmasia Indonesia. 2013.11(2):160-6.

16. Djamil R, Bakriyyah F. Isolasi dan identifi kasi jenis senyawa fl avonoid dalam fase n-butanol daun murbei (Morus alba L.) secara spektrofotometri. Jurnal Ilmu Kefarmasian Indonesia. 2015.13(2):194-200.

17. Nedialkova D, Naidenova M. Screening the antimicrobial activity of Actinomycetes strains isolated from Antarctica. Journal of Culture Collections. 2005.4:29-35.

18. Yukti APPH. Pengaruh ekstrak daun mengkudu (Morinda citrifolia L) terhadap pertumbuhan jamur penyebab ketombe Pityrosporum ovale secara in vitro [Skripsi]. Malang: Universitas Negeri Malang. 2011.

19. Soraya AI, Peramiarti IDSAP, Boenjamin RB. Efektivitas kombinasi ekstrak buah mengkudu (Morinda citrifolia) dan selenium sulfi da terhadap penghambatan pertumbuhan koloni Pityrosporum ovale. Mandala of Health. 2011.5(2):5p.

20. Susanti T. Pengaruh pemanfaatan buah mengkudu (Morinda citrifolia L) terhadap penyembuhan ketombe kering [Skripsi]. Padang: Universitas Negeri Padang. 2013.

21. Abdurrazaq. 10 cara tepat mengatasi ketombe. 2011. Diakses : 10 Maret 2016. http://ncca19.wordpress. com/2011/03/14/10-cara-tepat-mengatasi-ketombe/

22. Purwantiningsih TI, Suranindyah YY, Widodo. Aktivitas senyawa fenol dalam buah mengkudu (Morinda citrifolia) sebagai antibakteri alami untuk penghambatan bakteri penyebab mastitis. Buletin Peternakan. 2014.38(1):59-64.
Published
2017-04-30
How to Cite
AMBARWATI, AMBARWATI; SUJONO, TANTI AZIZAH; SINTOWATI, RETNO. Combination extracts of Pandan Wangi Leaves (Pandanus amaryllifolius Roxb.) and Mengkudu Fruits (Morinda citrifolia) as Antifungal Against Fungi Causes Dandruff. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 15, n. 1, p. 96-101, apr. 2017. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/491>. Date accessed: 22 dec. 2024.
Citation Formats
Issue
Vol 15 No 1 (2017): JIFI
Section
Articles
License

Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.

This licence applies to Author(s) and Public Reader means that the users mays :

  • SHARE:
    copy and redistribute the article in any medium or format
  • ADAPT:
    remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication)
  • ALIKE:
    If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original.
  • NO ADDITIONAL RESTRICTIONS:
    You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

It does however mean that when you use it you must:

  • ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

You may not:

  • NONCOMMERCIAL: You may not use the article for commercial purposes.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.