Penapisan Fitokimia dan Uji Hayati secara BSLT dari Daun, Buah dan Biji Phaleria macrocarpa

  • Suci Eka Lestari Universitas Pancasila
  • Ratna Djamil Universitas Pancasila

Abstract

Mahkota Dewa (Phaleria macrocarpa [Scheff] Boerl), is Indonesian herb that famous for its medicinal activity. The chemical constituens of the leaves, fruits and seeds have been examined, and BSLT (brine shrimp lethality test) have been carried out. On phytochemical screening, the leaves showed the existence of: volatile oil, sterol, triterpene, higher fatty acid, alkaloid, flavon aglycon, coumarine, tannin, steroid glycoside, flavonoid, polyuronide and triterpene, the fruits contain: volatile oil, sterol, triterpene, higher fatty acid, alkaloid, flavon aglycon, coumarine, tannin, reducing compound, steroid glycoside, flavonoside, polyuronide and saponine; while the seeds contain: steroid, triterpene, higher fatty acid, alkaloid, flavon aglycon, coumarine, tannin, reducing compound, steroid glycoside and flavonoid. Brine shrimp lethality test showed that the LCs of the n-hexane fraction of the leaves, fruits and seeds are 2.34 ppm, 32.62 ppm and 4.33 10-28 ppm respectively; the aethyl acetate fraction of the leaves, fruits and seeds are 10.55 ppm, 29,12 ppm and 4.71 ppm respectively; while the methanol fraction of the leaves, fruits and seeds are 1.46.10-5ppm, 39.32 ppm, and 53.31 ppm respectively. From this study it may be concluded that the n-hexane and aethyl acetate fraction of the seeds have the most active compounds, while the leaves have the most active compounds in the ethyl acetate fraction.

References

1. Mahkota dewa tanaman obat. diambil dari http:// agritekno.tripod.com/mahkota_dewa.com. diakses 1 oktober, 2004.

2. Harmanto N. Mahkota dewa obat pusaka para dewa. Revisi. Depok: Agromedia Pustaka; 2004. hal.25-9.

3. Dalimartha S. Atlas tumbuhan obat indonesia. Jilid 3. Jakarta: Puspa Swara; 2003. hal. 65-2.

4. Hertiani T, Retno WP, Pebriati S. Uji toksisitas ekstrak daun dan biji Phaleria macrocarpa (Scheff.) Boerl. dengan metode BSLT. Pharmacon. 2002.3(1):10-7.

5. Meyer BN, Ferrigni NR, Putnam JE, Jacobsen L.B, Nichols DE and McLaughlin JL. Brine shrimp: a convinient general bioassay for active plant constituents. Planta Medica. 1982.45(1):3-31.

6. Rumiyati, Sismindari, Widyastuti SM. Toksisitas ekstrak air tubuh buah Ganoderma sp. terhadap larva udang Artemia salina Leach. Majalah Farmasi Indonesia. 2002. 13(1): 44-8.

7. Hertiani T, Silvia U. Uji toksisitas kulit batang makutadewa (Phaleria macrocarpa (Scheff.) Boerl.) terhadap Artemia salina Leach dan profil kromatografi lapis tipis fraksi aktif. Majalah Farmasi Indonesia. 2002. 13(2): 65-9, 105-101.

8. Ciulei. Methodology for analysis of vegetable and drugs. Bucharest: Faculty of Pharmacy Rumania. p.2611.
How to Cite
LESTARI, Suci Eka; DJAMIL, Ratna. Penapisan Fitokimia dan Uji Hayati secara BSLT dari Daun, Buah dan Biji Phaleria macrocarpa. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 3, n. 2, p. 70-73, sep. 2005. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/610>. Date accessed: 23 june 2024.
Section
Articles