Pengaruh Iradiasi Sinar Gamma dan Konsentrasi Kitosan terhadap Pembentukan Hidrogel Polivinil Alkohol-Kitosan

  • Zuhelmi Aziz Universitas Pancasila
  • Gatot Trimulyadi Patir Batan
  • Trivena Fithriany A Universitas Pancasila

Abstract

Chitosan is one of the product from the shrimp disposal. Its medicinal and pharmaceutics application are now developed by pharmaceutical industries, i.e as bioplastics and hydrogel. A research about the effect of gamma radiation and chitosan as a raw material for production of polyvinilalcohol has been carried out. PVA-chitosan hydrogel was made from a mixture of composition of 80% PVA in 10% solution and 20% of chitosan in 0, 1, 2 ,and 3% solution respectively. The mixture was heated in oven at 80°C for two hours and then irradiated with 0, 15, 25, and 35 kGy gamma radiation. The physical characteristic of the gel was determined, e.g. colour, swelling degree and gel fraction. The colour of hydrogel more yellow darker to raising of chitosan concentration and radiation dosage. Swelling degree PVA-chitosan hydrogel increased meanwhile chitosan concentration and radiation dosage decreased. In absolute ethanol medium (96%) PVA-chitosan hydrogel was deswelling. The swelling degree PVAchitosan hydrogel decreased with increased gel fraction.

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How to Cite
AZIZ, Zuhelmi; TRIMULYADI, Gatot; A, Trivena Fithriany. Pengaruh Iradiasi Sinar Gamma dan Konsentrasi Kitosan terhadap Pembentukan Hidrogel Polivinil Alkohol-Kitosan. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 3, n. 2, p. 74-81, sep. 2005. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/611>. Date accessed: 23 june 2024.
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