Efek Kurkumin terhadap Aktivitas Enzim Glutation Peroksidase Mitokondria Hati Tikus

  • Syamsudin Syamsudin Universitas Pancasila
  • Suyatna FD Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia
  • Ganiswarna S Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia
  • Sadikin M Bagian Biokimia Fakultas Kedokteran Universitas Indonesia

Abstract

This study was conducted to prove the hypothesis that Curcumin could prevent the oxidative damage of rat liver mitochondria induced by t-butylhydroperoxide (t-BHP). The induction of 400 uMt-BHP reduced Gluthatione Peroxidase (GPx) activity from (0.29+0.03) to (0.04+0.01) umol/min/mg protein. Instillation of Curcumin of 1000 uM could elevate GPx activity to (0.16+0.002) umol/min/mg protein.

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How to Cite
SYAMSUDIN, Syamsudin et al. Efek Kurkumin terhadap Aktivitas Enzim Glutation Peroksidase Mitokondria Hati Tikus. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 2, n. 2, p. 77-80, apr. 2004. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/631>. Date accessed: 24 may 2025.
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