Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits

  • Paulina Veronika Yamlean Universitas Sam Ratulangi
  • Edwin De Queljoe Universitas Sam Ratulangi
  • Widdhi Bodhi Universitas Sam Ratulangi

Abstract

Candlenut plant in Indonesia is still limited to traditional uses such as cooking spices and traditional medicines. Only a few research has been done on Candlenut oil. The purpose of this study is to make ointment base variations toward the quality of Candlenutoil ointment with 12.5% concentration andits healing potential teston open wounds in rabbits infected with the Staphylococcus aureus bacteria. This research method is a laboratory experiment using 3 variations of base ointment namely hydrocarbon base, absorption base and water soluble base with Candlenut oil test solution of 12.5%. The results showed the quality test of the ointment with three variations of ointment base fulfilled the requirements of organoleptic test, homogeneity test, and pH test, but Candlenutoil ointment of 12.5% with hydrocarbon base did not meet the scattering power requirement. The results of the ANOVA test showed no significant difference between the base variations of the ointment and the size of wound healing. This shows that the three variations of the 12.5% Candlenut oil ointment base can be used in healing open wounds on rabbits (Oryctolagus cuniculus) infected with the Staphylococcus aureus bacteria.

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Published
2019-10-29
How to Cite
YAMLEAN, Paulina Veronika; QUELJOE, Edwin De; BODHI, Widdhi. Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 17, n. 2, p. 232-237, oct. 2019. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/647>. Date accessed: 18 nov. 2019. doi: https://doi.org/10.35814/jifi.v17i2.647.
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Articles