Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits

  • Paulina Veronika Yamlean Universitas Sam Ratulangi
  • Edwin De Queljoe Universitas Sam Ratulangi
  • Widdhi Bodhi Universitas Sam Ratulangi
DOI: https://doi.org/10.35814/jifi.v17i2.647

Abstract

Candlenut plant in Indonesia is still limited to traditional uses such as cooking spices and traditional medicines. Only a few research has been done on Candlenut oil. The purpose of this study is to make ointment base variations toward the quality of Candlenutoil ointment with 12.5% concentration andits healing potential teston open wounds in rabbits infected with the Staphylococcus aureus bacteria. This research method is a laboratory experiment using 3 variations of base ointment namely hydrocarbon base, absorption base and water soluble base with Candlenut oil test solution of 12.5%. The results showed the quality test of the ointment with three variations of ointment base fulfilled the requirements of organoleptic test, homogeneity test, and pH test, but Candlenutoil ointment of 12.5% with hydrocarbon base did not meet the scattering power requirement. The results of the ANOVA test showed no significant difference between the base variations of the ointment and the size of wound healing. This shows that the three variations of the 12.5% Candlenut oil ointment base can be used in healing open wounds on rabbits (Oryctolagus cuniculus) infected with the Staphylococcus aureus bacteria.

References

1. Ginting M, Surbakti D, Thamrin. Sintesis dan karakteristik senyawa polihidroksi yang diperoleh melalui epsoksidasi minyak kemiri. Jurnal Penelitian MIPA. 2008. 2 (1) 1

2. Krisnawati, H. Kallo.M dan Kanninen. M.. Aleurites moluccana (L) Willd. Ecology. Silviculture and Prodictivity. CCIFOR.Bogor. Indonesia. 2011. Hal 1-4

3. Heyne K, 1987. Diambil dari: URL: https://id.wikipedia.org/wiki/Kemiri. Diakses tanggal 15 Agustus 2018.

4. Izemi1, B. Boy Rahardjo Sidharta, Yanuartono. Potensi Sediaan Cair Ekstrak Campuran Kemiri (Aleurites moluccana L.) dan Kedelai (Glycine max (L.) Merill) sebagai Penumbuh Rambut. e-journal.uajy.ac.id/8622. 2015. Hal 1-11

5. Richa Yuswantina, Istianatus Sunnah dan I Nyoman Dwika Dharmanta. 2014. Diakses tanggal 3 Agustus 2018. Kode Jurnal: jpfarmasidd140494.

6. Pongsipulung Grace. 2013..diambil dari URL:https://ejournal.unsrat.ac.id/index.php/pharmacon/article/view/462/370. Diakses tanggal 2 Agustus 2018.

7. Lachman, Leon. Teori dan Praktek Farmasi Industri. UI-Press : Jakarta 2008.

8. Astuti I. Y., D. Hartanti, dan Aminiati A. Peningkatan Aktivitas Antijamur Candida albicans Salep Minyak Atsiri Daun Sirih (Piper bettle LINN.) melalui Pembentukan Kompleks Inklusi dengan β-siklodekstrin. Majalah Obat Tradisional. 2010. Hal 94-99

9. Akhtar. N.,Adnan, Q. Ahmad, M. Mehmood, A.,Farzana, K. Rheological studies and characterization of different oil. J. Chem. 2009. Soc.Pak.31(2).Hal. 201-206

10. Hasyim. N. K.L, Pare. I, Junaid, Kurniati A. Formulasi dan Uji Efektivitas Gel Luka Bakar Ekstrak Daun Cocor Bebek (Kalanchoe pinnata L.) pada Kelinci (Oryctolagus cuniculus). Majalah Farmasi dan Farmakologi. 16(2) : 2012. Hal 89-94

11. Ginting, M. Surbakti, D, Thamrin. Sintesis dan Karakterisasi Senyawa Polihidroksi yang diperoleh melalui Epoksidasi Minyak Kemiri. Jurnal Penelitian MIPA (2) . 2008. 1.,1

12. Naibaho. H. Olivia. 2013. Diambil dari https://ejournal.unsrat.ac.id/index.php/pharmacon/article/view/1553. Diakses tanggal 30 Mei 2018.
Published
2019-10-29
How to Cite
YAMLEAN, Paulina Veronika; QUELJOE, Edwin De; BODHI, Widdhi. Base Variations of the Candlenut Oil Ointment (Aleurites moluccana) and the Healing Potential Test on Wounds in Rabbits. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 17, n. 2, p. 232-237, oct. 2019. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/647>. Date accessed: 26 apr. 2024. doi: https://doi.org/10.35814/jifi.v17i2.647.
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Vol 17 No 2 (2019): JIFI
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