Rationality Evaluation of Antihypertension Drug Use in dr. Soegiri Hospital Lamongan at 2017

  • Dian Sa'idah Universitas Islam Negeri Maulana Malik Ibrahim Malang
  • Hajar Sugihantoro Universitas Islam Negeri Maulana Malik Ibrahim Malang
  • Abdul Hakim Universitas Islam Negeri Maulana Malik Ibrahim Malang
  • Siti Maimunah Universitas Islam Negeri Maulana Malik Ibrahim Malang
DOI: https://doi.org/10.35814/jifi.v17i1.650

Abstract

Hypertension is a non-communicable disease characterized by increased blood pressure that reaches > 140/90 mmHg. The incidence of hypertension and its complications continues to increase every year so the potential for irrational use of drugs is also increasing.  The purpose of this study was to determine the rationality of the use of antihypertensive drugs at the outpatient installation of Hospital Dr. Soegiri Lamongan in the 2017 period, which reviews the exact indication, the right patient, the right drug, and the right dosage. This study is an observational study conducted by descriptive method and uses retrospective data, namely medical record sheets of hypertensive patients in 2017.  The sampling method used was proportional stratified random sampling. The study population was 451 medical records of hypertensive patients, the number of samples used was 82 medical records where there were 269 prescription sheets in it. The data obtained are then compared using the 2013 American Society of Hypertension (ASH) literature and 2017 Hypertension Clinical Guidelines. The results showed that the rationality of the use of antihypertensive drugs in Dr. Soegiri Lamongan Hospital in 2017 period is 100% accurate on indications, 91,82 % right on patients, 88,85% right on drugs, and 98,14% right on dosages.

References

1. Katzung, B.G., Susan, B.M., dan Anthony, J.T. 2004. Basic and Clinical Pharmacology 10th Edition. China: The McGraw-Hill Companies Inc

2. Florensia, A. 2016. Evaluasi Penggunaan Obat Antihipertensi Di Instalasi Rawat Inap RSUD Kota Tangerang Dengan Metode Anatomical Therapeutic Chemical/Defined Daily Dose Pada Tahun 2015. [skripsi]. Jakarta: Program Studi Farmasi

3. Chobanian, A.V., George, L.B., Henry, R.B., William, C.C., Lee, A.G., et al. 2004. Seventh Report Of The Joint National Committee On Prevention, Detection, Evaluation, And Treatment of High Blood Pressure. Journal Of The American Heart Association. 42: 1206-1252

4. [Riskesdas] Riset Kesehatan Dasar. 2007. Jakarta: Badan Penelitian Pengembangan Kesehatan Departemen Kesehatan RI

5. [Riskesdas] Riset Kesehatan Dasar. 2013. Jakarta: Badan Penelitian Pengembangan Kesehatan Departemen Kesehatan RI

6. Kemenkes RI. 2011. Modul Penggunaan Obat Rasional. Jakarta: Kementrian Kesehatan Republik Indonesia

7. Depkes RI. 2006. Pharmaceutical Care Untuk Penyakit Hipertensi. Ditjen Bina Kefarmasian Dan Alat Kesehatan Departemen Kesehatan

8. Budiman., Rosmariana, S., Paramita P. 2015. Hubungan Dislipidemia, Hipertensi, dan Diabetes Mellitus dengan Kejadian Infark Miokard Akut. Jurnal Kesehatan Masyarakat Andalas. Vol 10 (1) hal 32-37

9. American Heart Association. 2011. Heart International Cardiovascular Disease Statistic. [online] http://www.american.heart.org/ Diakses tanggal 11 Januari 2018

10. Creager, M.A., Luscher, T.F., Cosentino, F., Beckman, J.A. 2003. Diabetes and Vascular Disease: Pathophysiology, Clinical Consequences, and Medical Therapy. Circulation. 108:1527-1529

11. Sargowo, D. 2012. Single Pill Combination in Antihypertensine Therapy. Malang: Fakultas Kedokteran Universitas Brawijaya [online] http://djanggan.lecture.ub.ac.id/files/2012/07/Single-Pill-Combination-in-Antihypertensive-Therapy.doc

12. Chi, C., Chenhui, T., Bin, B., Shikai, Y., Marianna, K. 2016. Angiotensin System Blockade Combined with Calcium Channel Blocker is Superior the Other Combinations in Cardiovascular Protection with Similar Blood Pressure Reduction: A Meta-Analysis in 20,451 Hypertensive Patiens. The Journal of Clinical Hypertension. (18 no 8)

13. Syamsudin. 2011. Interaksi Obat Konsep Dasar dan Klinis. Jakarta: UI Press.

14. Sumawa, P.M.R., Adeanne C.W., dan Paulina V.Y.Y. 2015. Evaluasi Kerasionalan Penggunaan Obat Antihipertensi Pada Pasien Hipertensi Rawat Inap Di RSUP Prof. Dr. R. D. Kandou Manado Periode Januari-Juni 2014. Jurnal Ilmiah Farmasi. Vol 4 No 3

15. BPOM RI. 2014. Pusat Informasi Obat Nasional. [online] http://pionas.pom.go.id/ioni. Diakses 12 Juni 2018

16. Kowalski, R. E. 2010. Terapi Hipertensi Program 8 Minggu, terjemahan oleh Rani S. E. Bandung: Qanita.

17. Brunton, L., Bruce, C., Bjorn, K. 2011. Goodman and Gilman’s The Farmacological Basis of Therapeutics 12th Edition. New York: McGraw Hill Medical

18. Anonim.2017, Guideline for the Prevention, Detection, Evaluation, and Management of High
Blood Pressure in Adults. Clinical Practice Guidelinne (Tersedia di https://goo.gl/oQeHRg )
Published
2019-04-24
How to Cite
SA'IDAH, Dian et al. Rationality Evaluation of Antihypertension Drug Use in dr. Soegiri Hospital Lamongan at 2017. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 17, n. 1, p. 107-113, apr. 2019. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/650>. Date accessed: 22 dec. 2024. doi: https://doi.org/10.35814/jifi.v17i1.650.
Citation Formats
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Vol 17 No 1 (2019): JIFI
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