STRATEGI PENCARIAN SENYAWA BIOAKTIF BARU DARI SUMBER BAHAN ALAMI TUMBUHAN
Abstract
Plants provide enormous chemical diversity. Advances in bioassay screening, isolation techniques and structural elucidation have shortened and facilited the process of drug discovery from Indonesian medicinal plants. It is now general practice among natural product chemist and others field to use some strateg: for investigate bioactive compounds from natural product.
References
1. Croasman WR, Carlson RM. Two dimensional NMR spectroscopy, spplication for chemists and biochemists. VCH Publishing; 1994.
2. Derome AE. Modern NMR techniques for chemistry research. Pergamon Press; 1988.
3. Geran RI, Greenberg NH, McDonald MM, Schumacher AM, Abbott BJ. Protocols for screening chemical agents and natural product against animal tumors and other biological systems, cancer chemotheraphy reports 3; 1972.
4. Gupta MM, Jain DC, Mathur AK, Singh AK, Verma RK, Kumar S. Planta medica 62;1996.
5. Harborne JB. Metode fitokimia penuntun caramodern menganalisis tumbuhan. Bandung: ITB; 1987.
6. Hostettmann K, Hamburger M, Hostettmann M, Marston A. New developments in the separation of natural products In : Fischer NH, Isman MB, Stafford HA. Modern phytochemical methods. Plenum Press;1991.
7. Hostettmann K, Hostettmenn M, Marston A. Preparative chromato-graphic techniques : application in natural products isolation. Belin: Springer-Verlag; 1986.
8. Huxtable RJ. The pharmacology of extinction, journal of ethnopharmacology 37. 1992.
9. Kitagawa I, Shibuya H. Pharmacochemical investigation of Indonesian medicinal plants In : Hastettmenn et al. Phytochemistry of plants used in traditional medicine. Clarendon Press-Oxford; 1995.
10. Kitagawa I, Simanjuntak P, Hori K, Nagami N, Mahnud T, Shibuya H, Kobayashi M. Indonesian medicinal plant vii. seven new clerodane-type diterpenoids, peronemins a2, a3, 61, 62, 63, cl, and dl from the leaves of Peronema canescens (Verbenaceae). Chem. Pharm. Bull. 42; 1994.
11. Marston A, Hostettmenn K. Modern separation method, natural product reports 8. 1991.
12. Mayer BN, Ferigni JT, Putnam LB, Jacobsen DE, Nichols DE, McLaughin JL. Brine shrimp, a convenient general bioassay for active plant constituent. Planta Medica 95; 1995.
13. Rifai MA, Anggadiredja J, Keanekaragaman plasma nuftah tumbuhan obat indonesia, penanganan penelitian, pengembangan, pemanfaatan dan pelestariannya. Buletin DRN 30; 1996.
14. Schroeder DR, Nakanishi K. Journal of natural product 50.1987.
15. Shoemaker RJ, Monks A, Alley MC, Scudiero DA, Fine DL, McLamore TL, Abbott BJ, Paull KD, Mayo JG, Boyd MR. Development of human tumor cell line panels for use in disease-oriented drug screening. In : Hall TC. Prediction of response to cancer therapy. 1988.
16. Silverstein RM, Bassler C, Morrill TC. Spectrometric identification of organic compounds. John Wiley & Sons; 1981.
17. Swindell CS, Krauss NE. Biologically active taxol analogues with delete a ring side substituents and variable C-2' configurated. Med. Chem. 34; 1991.
18. Tan RX, Zheng WF, Tang HQ. Biologically active substances from the Genus Artemisia. Planta Medica 64; 1998.
19. Wani MC, Taylor HL, Wall ME, Coggum P, McPhail AT. Plant antitumor agents VI. The isolation and structure of antitumor of taxol, A novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Soc. 93; 1991.
2. Derome AE. Modern NMR techniques for chemistry research. Pergamon Press; 1988.
3. Geran RI, Greenberg NH, McDonald MM, Schumacher AM, Abbott BJ. Protocols for screening chemical agents and natural product against animal tumors and other biological systems, cancer chemotheraphy reports 3; 1972.
4. Gupta MM, Jain DC, Mathur AK, Singh AK, Verma RK, Kumar S. Planta medica 62;1996.
5. Harborne JB. Metode fitokimia penuntun caramodern menganalisis tumbuhan. Bandung: ITB; 1987.
6. Hostettmann K, Hamburger M, Hostettmann M, Marston A. New developments in the separation of natural products In : Fischer NH, Isman MB, Stafford HA. Modern phytochemical methods. Plenum Press;1991.
7. Hostettmann K, Hostettmenn M, Marston A. Preparative chromato-graphic techniques : application in natural products isolation. Belin: Springer-Verlag; 1986.
8. Huxtable RJ. The pharmacology of extinction, journal of ethnopharmacology 37. 1992.
9. Kitagawa I, Shibuya H. Pharmacochemical investigation of Indonesian medicinal plants In : Hastettmenn et al. Phytochemistry of plants used in traditional medicine. Clarendon Press-Oxford; 1995.
10. Kitagawa I, Simanjuntak P, Hori K, Nagami N, Mahnud T, Shibuya H, Kobayashi M. Indonesian medicinal plant vii. seven new clerodane-type diterpenoids, peronemins a2, a3, 61, 62, 63, cl, and dl from the leaves of Peronema canescens (Verbenaceae). Chem. Pharm. Bull. 42; 1994.
11. Marston A, Hostettmenn K. Modern separation method, natural product reports 8. 1991.
12. Mayer BN, Ferigni JT, Putnam LB, Jacobsen DE, Nichols DE, McLaughin JL. Brine shrimp, a convenient general bioassay for active plant constituent. Planta Medica 95; 1995.
13. Rifai MA, Anggadiredja J, Keanekaragaman plasma nuftah tumbuhan obat indonesia, penanganan penelitian, pengembangan, pemanfaatan dan pelestariannya. Buletin DRN 30; 1996.
14. Schroeder DR, Nakanishi K. Journal of natural product 50.1987.
15. Shoemaker RJ, Monks A, Alley MC, Scudiero DA, Fine DL, McLamore TL, Abbott BJ, Paull KD, Mayo JG, Boyd MR. Development of human tumor cell line panels for use in disease-oriented drug screening. In : Hall TC. Prediction of response to cancer therapy. 1988.
16. Silverstein RM, Bassler C, Morrill TC. Spectrometric identification of organic compounds. John Wiley & Sons; 1981.
17. Swindell CS, Krauss NE. Biologically active taxol analogues with delete a ring side substituents and variable C-2' configurated. Med. Chem. 34; 1991.
18. Tan RX, Zheng WF, Tang HQ. Biologically active substances from the Genus Artemisia. Planta Medica 64; 1998.
19. Wani MC, Taylor HL, Wall ME, Coggum P, McPhail AT. Plant antitumor agents VI. The isolation and structure of antitumor of taxol, A novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Soc. 93; 1991.
How to Cite
SIMANJUNTAK, Partomuan.
STRATEGI PENCARIAN SENYAWA BIOAKTIF BARU DARI SUMBER BAHAN ALAMI TUMBUHAN.
JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 1, n. 2, p. 73-77, sep. 2003.
ISSN 2614-6495.
Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/658>. Date accessed: 05 nov. 2024.
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