Aplikasi Spektrometri Resonansi Magnet Inti 2-Dimensi Untuk Analisis Tumbuhan Obat Tradisional Indonesia

  • Partomuan Simanjuntak Pusat Penelitian Bioteknologi-LIPI

Abstract

Caesalpinia major Dandy ex Excell is one of the traditional medicinal plants from Nusa Tenggara Timur Province (Flores island, Ruteng) which the local people called as “Dekar". The root of this plant is used as anthelmintic, anti rheumatic, back-ache and also as tonic. Chemical structure elucidation of isolated compound from C. major caesaldekarin A has been done and it's based on ultraviolet, infrared, nuclear nagnetic resonance and mass spectrometry: To know the correlation between proton and proton, proton and carbon, carbon and carbon, NMR two dimensional (2D) have been also interpreted by the data of 'H-'H COSY, 13C-'H COSY, COLOC, HMBC and INADEQUATE. The stereochemistry of the relative structure of caesaldekarin A is determined by 2D NMR NOESY.

References

1. Tampubolon, O (1990). Tumbuhan obat Indonesia, Lembaga Nasional Indonesia, LIPI, hal 1 - 3

2. Derome, A.E. (1988). Modern NMR Techniques for Chemistry Research, Pergamon Press, Oxford, pp. 97

3.Schraml, J., (1985). Two Dimensional NMR Spectroscopy, John Wiley & Sons, New York, pp. 145

4. Kitagawa, I., (1987). Research Report of naturally Occuring Drug Materials in Indonesia I, Osaka, Japan

5. Kitagawa, I, P. Simanjuntak, T. Watano, S. Fujii, Y. Yamagata and M. Kobayashi, (1994). Indonesian Medicinal Plants XI : Chemical Structure caesaldekarin a dan b. Two new cassane-type furanoditerpene from the roots Caesalpinia major (Fabaceae), Chem. Pharm. Bull., 42(9), 1798
Published
2003-04-29
How to Cite
SIMANJUNTAK, Partomuan. Aplikasi Spektrometri Resonansi Magnet Inti 2-Dimensi Untuk Analisis Tumbuhan Obat Tradisional Indonesia. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 1, n. 1, p. 1-7, apr. 2003. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/662>. Date accessed: 05 nov. 2024.
Section
Articles