Evaluation of Drug Side Effects Chemotherapy on Quality of Life (QOL) Breast Cancer Patients at Hospital X in Jakarta

  • Sondang Khairani Universitas Pancasila
  • Sesilia Andriani Keban Universitas Pancasila
  • Meyke Afrianty Universitas Pancasila

Abstract

Breast cancer is the number one cancer type discovered at women in the world. Most causes are genetic factors and hormonal factors. One cancer treatments with chemotherapy. Chemotherapy drugs active in cells dividing and reproducing, but cells normally to be affected by chemotherapy and side effects from chemotherapy drugs affect quality of life. The aim of the study to evaluate side effects of chemotherapy drugs on the quality of life of breast cancer patients. Sampling technique observational prospective breast cancer patients with completed the chemotherapy cycle from September 2017 to April 2018 with descriptive analysis and statistics by looking correlation between drug side effects and Quality of Life (QoL). Results of the study were side effects of fatigue 100%, nausea 67,5%, vomiting 60%, no appetite 63,75%, fever 42,5%, joint pain 43,75%, diarrhea 16,25%, difficulty swallowing 16,25%, allergies 5%, itching 1,25%, mouth sores 3,75%, swollen right hand 1,25%, constipation 3,75%. QoL results are physical 6,2%; psychology 5,3%; social 4,9%; spiritual 6,8%. Results of Sperman test showed no correlation between the side effects of chemotherapy and QoL P> 0,05. This study shows that there is no relationship between the side effects drug chemotherapy and QoL in breast cancer patients.

References

1. Bray F. Mc Carron, Parkin DM. Review. The Changing Global patterns of Female Breast Cancer Incidence and Mortality. Breast Cancer Research; 2004, h 229-39.

2. Tjindarbumi. Penanganan Kanker Payudara Masa Kini Dengan Berbagai Macam Isu di Indonesia. Proceending Indonesian Issues on Breast Cancer . Surabaya. 2004

3. Bakhtiar. Manfaat & Efek Samping Kemoterapi. Dapat diakses di http:// Manfaat dan efek samping kemoterapi¬_Bakhtiar.htm dibuka pada tanggal 28 Maret 2018. 2012

4. Saragi. Hubungan Dukungan Keluarga dengan Kualitas Hidup Klien Hemodialisa di rumah sakit H Adam Malik Medan. 2010. http://respository.usu.ac.id.diaksesn

5. Grunberg, Steven, M. Management of Nausea and Vomiting. 2007 http ://i.cmpnet.com/ cancernetwork/handbook/pdf/38nausea.pdf.

6. Kusminto, Deteksi Sangat Dini Kanker Payudara, Jawaban Untuk Menghindar. Departemen Kesehatan. 2006.

7. Australian Cancer Incidence And Mortality (ACIM) Breast Cancer. http://www.aihw.gov.au/acim- books/

8. Pherson K Mc, Steel CM, Breast Cancer Epidemiology Risk Factor and Genetic, BMJ. 2010; Vol 321 : 624-628

9. Carson, C. Exercise for Cancer Patients, HCA Cancer Care, Colorado 2002

10. Alam, S. Gambaran Kualitas Hidup Pasien Kanker Payudara Di Rsud Panembahan Senopati Bantul. Skripsi. 2017. Yogyakarta

11. Dersen W. Onkologi Klinis. Jakarta: Fakultas kedokteran universitas Indonesia. 2011

12. Ismail S. Metodologi penelitian kesehatan. 2009. Jakarta: PT. Rineka cipta.

13. Setyawati, S., Rosalina., Pranowati, P. Hubungan lama kemoterapi dengan kualitas hidup pasien kanker payudara di RSUD Tugurejo Semarang. 2014 PSIK ngudiwaluyo ungaran.

14. Betty, R, Ferrel. Quality of Life Instrument - Breast Cancer Patient Version City of Hope. United State. 1995.
Published
2019-04-24
How to Cite
KHAIRANI, Sondang; KEBAN, Sesilia Andriani; AFRIANTY, Meyke. Evaluation of Drug Side Effects Chemotherapy on Quality of Life (QOL) Breast Cancer Patients at Hospital X in Jakarta. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 17, n. 1, p. 9-13, apr. 2019. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/705>. Date accessed: 05 nov. 2024. doi: https://doi.org/10.35814/jifi.v17i1.705.
Section
Articles