Ethanolic Extract Effect of Parkia speciosa Peel to Hepar Function of Used Cooking Oil Exposed Rattus norvegicus

  • Fafa Nurdyansyah Prodi Teknologi Pangan Universitas PGRI Semarang
  • Dyah Ayu Widyastuti Pendidikan Biologi Universitas PGRI Semarang
  • Andita Ayu Mandasari Prodi Ahli Teknologi Laboratorium Medik Universitas Maarif Hasyim Latif

Abstract

The use of cooking oil repeatedly is one of liver damage trigger which usually be marked by
enhancement of SGPT and SGOT level. The objective of this study is to know the eff ect of P. speciosa peel
ethanolic extract in used cooking oil exposed Wistar rats (R. norvegicus). The indicator are SGPT and SGOT
concentration. Parkia speciosa peel was extracted then use to antioxidant source. Rattus norvegicus was divided into 4 group. Group 1 with no treatment, group 2 with 1 ml used cooking oil 118 mek/kg and 100 mg/l extract, group 3 with 1 ml used cooking oil 118 mek/kg and 200 mg/l extract, and group 4 as positive control with 1 ml used cooking oil 118 mek/kg. Each group serum sample was analyzed for SGPT and SGOT. The result showed that 200 mg extract treatment is signifi cantly bring lower SGPT and SGOT concentration compared to positive control. The higher dose of ethanolic extract of P. speciosa peel is highly prevent liver damage which indicated by the lower SGPT and SGOT concentration in serum. The ethanolic extract of P. speciosa peel has potential to ward off free radicals which caused by used cooking oil exposed. That fact was be marked by SGPT and SGOT decreasing persentage.

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Published
2021-04-30
How to Cite
NURDYANSYAH, Fafa; WIDYASTUTI, Dyah Ayu; MANDASARI, Andita Ayu. Ethanolic Extract Effect of Parkia speciosa Peel to Hepar Function of Used Cooking Oil Exposed Rattus norvegicus. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 1, p. 111-117, apr. 2021. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/795>. Date accessed: 20 june 2021. doi: https://doi.org/10.35814/jifi.v19i1.795.
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Articles