The Potency of Essential Oil and Components of KaempfeThe Potency of Essential Oil and Components of Kaempferia Pandurata as Slimming AromaTherapyria pandurata as Slimming Aromatherapy

  • Irma Hermawati Suparto
  • Rahmi Nur Wahidah Institut Pertanian Bogor
  • Irmanida Batubara Institut Pertanian Bogor

Abstract

Temu kunci (Kaempferia pandurata) is one of the Indonesian aromatic plants containing essential oils. The objective of this study was to evaluate the potential compound in temu kunci essential oils that has activities as slimming aromatherapy. Essential oil was obtained from the rhizome by distillation then further fractionated using column chromatography and obtained 7 fractions. Based on the gas chromatography mass spectrometer, the main component of the essential oil of temu kunci was o-cymene, while the main component in fraction 1 was limonene. Fraction 1, camphor and the essential oils were tested in vivo as slimming aromatherapy using adult male Sprague Dawley rats given for 5 weeks. Animals received inhalation of camphor and essential oils showed a higher tendency to increase body weight compared to animals given fraction 1. Animals treated with fraction 1 showed the lowest body weight gain response (47%) eventhough not significant, however it gave the lowest total consumption per weekly (P<0.05). Therefore, based on these results, fraction 1 that has limonene is potential as slimming aromatherapy agent.

References

1. Lean M, Lara J, O;Hill J. ABC of Obesity: Strategies for preventing obesity. J Brit Med.2006. 333.p 959-962 .

2. Dachriyanus, Delpa O, Rika O, Olivia E, Suhatri, Mukhtar MH. Efek a-mangostin terhadap kadar kolesterol LDL darah mencit putih jantan serta penentuan letal dosis 50 (LD50). J Sains Tek Far. 2007. 12(2). P. 64-72

3. Batubara I, Suparto I, Sadiah S. Matsuoka R, Mitsunaga T. Effect of Zingiver zerumbet essential oil and zerumbone inhalation on body weight of Sprague dawley rat. Pak J Biol Sci. 2013, 16(19). P 1028-1033.

4. Batubara I, Anggraeni A, Darusman LK.. Inhalasi aroma temulawak terhadap bobot badan tikus. Jurnal Bahan Alam Indonesia . 2013. Vol 8(3): 187-191

5. Batubara I, Wulandari R, Djauhari E, 2012. Minyak atsiri bangle (Zingiber purpurem) dan senyawa aktifnya sebagai pelangsing aromaterapi secara in vivo. Pemenang III Kategori Peneliti Riset-MTIC Award.

6. Darusman, L.K., Batubara, I. Utami, M.R. 2014. Fractionation of Active Components from Piper cf. fragile Essential Oil as Aromatherapy for Anti-Obesity. Acta Hort. (ISHS) 1023:23-28

7. Hasim F, Batubara I, Suparto IH, 2016. The potency of Clove (Syzygium aromaticum) essential oil as slimming aromatherapy by in vivo assay. International Journal of Pharma and Bio Science. 7(1):110-116

8. Hayani E. Pemisahan komponen rimpang temukunci menggunakan kromatografi kolom. J Teknik Pertanian. 2007. 12. P. 35-37

9. Hariana A. Tumbuhan Obat dan Khasiatnya. Jakarta:Penebar Swadaya. 2007

10. Yun JM, Kweon HJ, Hwang JK, Mukhtar H. Induction of apoptosis and cell cycle arrest by a chalcone panduratin isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145. J Carc Ad Acc 2006. 27(7). P 1454-1464

11. Kim YD, Kim SM, Kim BM, Hwang JK, Sa KB. Boesenbergia pandurata attenuates diet-induced obesity by activating AMP-activated protein inase and regulating lipid metabolism. J Mol Sci Int. 2012. 13(1). P.994-1005

12. Miksusanti, Laksmi BS, Ponco B, Syarif R, Mulyadi GT, Yusuf S. Aktivitas antibakteri minyak atsiri temu kunci terhadap Pseudomonas aerugenose dan aplikasinya dalam film edible pati sagu. J Penelitian Sain. 2007. 10(3). P 345-354.

13. Sun J. D-limonene: safety and clincial application. J Alt Med. 2007. 12(3) p 259-264.

14. Shen J. Nijima A, Tanida M, Horri Y, Maeda K, Nagai K. Olfactory stimulation with scent of grapefruit oil affects autonomic nerves, lipolysis and appetite in rats. Neurosci Lett. 2005. 380. P. 289-294

15. Mursito B. Ramuan untuk Pelangsing Tubuh. Jakarta:Penebar Swadaya. 2007.

16. Baumans V. Environmental enrichment for laboratory rodents and rabbits: Rquirements of rodents, rabbits and research. ILAR Journal. 2005. 46(2). P 162-170.
Published
2020-04-28
How to Cite
SUPARTO, Irma Hermawati; WAHIDAH, Rahmi Nur; BATUBARA, Irmanida. The Potency of Essential Oil and Components of KaempfeThe Potency of Essential Oil and Components of Kaempferia Pandurata as Slimming AromaTherapyria pandurata as Slimming Aromatherapy. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 18, n. 1, p. 130-135, apr. 2020. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/845>. Date accessed: 19 oct. 2020. doi: https://doi.org/10.35814/jifi.v18i1.845.
Section
Articles