The Potency of Essential Oil and Components of KaempfeThe Potency of Essential Oil and Components of Kaempferia Pandurata as Slimming AromaTherapyria pandurata as Slimming Aromatherapy
Abstract
Temu kunci (Kaempferia pandurata) is one of the Indonesian aromatic plants containing essential oils. The objective of this study was to evaluate the potential compound in temu kunci essential oils that has activities as slimming aromatherapy. Essential oil was obtained from the rhizome by distillation then further fractionated using column chromatography and obtained 7 fractions. Based on the gas chromatography mass spectrometer, the main component of the essential oil of temu kunci was o-cymene, while the main component in fraction 1 was limonene. Fraction 1, camphor and the essential oils were tested in vivo as slimming aromatherapy using adult male Sprague Dawley rats given for 5 weeks. Animals received inhalation of camphor and essential oils showed a higher tendency to increase body weight compared to animals given fraction 1. Animals treated with fraction 1 showed the lowest body weight gain response (47%) eventhough not significant, however it gave the lowest total consumption per weekly (P<0.05). Therefore, based on these results, fraction 1 that has limonene is potential as slimming aromatherapy agent.
References
2. Dachriyanus, Delpa O, Rika O, Olivia E, Suhatri, Mukhtar MH. Efek a-mangostin terhadap kadar kolesterol LDL darah mencit putih jantan serta penentuan letal dosis 50 (LD50). J Sains Tek Far. 2007. 12(2). P. 64-72
3. Batubara I, Suparto I, Sadiah S. Matsuoka R, Mitsunaga T. Effect of Zingiver zerumbet essential oil and zerumbone inhalation on body weight of Sprague dawley rat. Pak J Biol Sci. 2013, 16(19). P 1028-1033.
4. Batubara I, Anggraeni A, Darusman LK.. Inhalasi aroma temulawak terhadap bobot badan tikus. Jurnal Bahan Alam Indonesia . 2013. Vol 8(3): 187-191
5. Batubara I, Wulandari R, Djauhari E, 2012. Minyak atsiri bangle (Zingiber purpurem) dan senyawa aktifnya sebagai pelangsing aromaterapi secara in vivo. Pemenang III Kategori Peneliti Riset-MTIC Award.
6. Darusman, L.K., Batubara, I. Utami, M.R. 2014. Fractionation of Active Components from Piper cf. fragile Essential Oil as Aromatherapy for Anti-Obesity. Acta Hort. (ISHS) 1023:23-28
7. Hasim F, Batubara I, Suparto IH, 2016. The potency of Clove (Syzygium aromaticum) essential oil as slimming aromatherapy by in vivo assay. International Journal of Pharma and Bio Science. 7(1):110-116
8. Hayani E. Pemisahan komponen rimpang temukunci menggunakan kromatografi kolom. J Teknik Pertanian. 2007. 12. P. 35-37
9. Hariana A. Tumbuhan Obat dan Khasiatnya. Jakarta:Penebar Swadaya. 2007
10. Yun JM, Kweon HJ, Hwang JK, Mukhtar H. Induction of apoptosis and cell cycle arrest by a chalcone panduratin isolated from Kaempferia pandurata in androgen-independent human prostate cancer cells PC3 and DU145. J Carc Ad Acc 2006. 27(7). P 1454-1464
11. Kim YD, Kim SM, Kim BM, Hwang JK, Sa KB. Boesenbergia pandurata attenuates diet-induced obesity by activating AMP-activated protein inase and regulating lipid metabolism. J Mol Sci Int. 2012. 13(1). P.994-1005
12. Miksusanti, Laksmi BS, Ponco B, Syarif R, Mulyadi GT, Yusuf S. Aktivitas antibakteri minyak atsiri temu kunci terhadap Pseudomonas aerugenose dan aplikasinya dalam film edible pati sagu. J Penelitian Sain. 2007. 10(3). P 345-354.
13. Sun J. D-limonene: safety and clincial application. J Alt Med. 2007. 12(3) p 259-264.
14. Shen J. Nijima A, Tanida M, Horri Y, Maeda K, Nagai K. Olfactory stimulation with scent of grapefruit oil affects autonomic nerves, lipolysis and appetite in rats. Neurosci Lett. 2005. 380. P. 289-294
15. Mursito B. Ramuan untuk Pelangsing Tubuh. Jakarta:Penebar Swadaya. 2007.
16. Baumans V. Environmental enrichment for laboratory rodents and rabbits: Rquirements of rodents, rabbits and research. ILAR Journal. 2005. 46(2). P 162-170.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Licencing
All articles in Jurnal Ilmu Kefarmasian Indonesia are an open-access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License which permits unrestricted non-commercial used, distribution and reproduction in any medium.
This licence applies to Author(s) and Public Reader means that the users mays :
- SHARE:
copy and redistribute the article in any medium or format - ADAPT:
remix, transform, and build upon the article (eg.: to produce a new research work and, possibly, a new publication) - ALIKE:
If you remix, transform, or build upon the article, you must distribute your contributions under the same license as the original. - NO ADDITIONAL RESTRICTIONS:
You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
It does however mean that when you use it you must:
- ATTRIBUTION: You must give appropriate credit to both the Author(s) and the journal, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
You may not:
- NONCOMMERCIAL: You may not use the article for commercial purposes.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.