Test Anti-Inflammatory and Analgesic Effect from Decoction of Bamboo Kuning Leaves (Bambusa Vulgaris Schard

  • Sondang Khairani
  • Lestari Rahayu Fakultas Farmasi, Universitas Pancasila
  • Ni Made Sandhiutami Fakultas Farmasi, Universitas Pancasila
  • Rika Sari Dewi Fakultas Farmasi, Universitas Pancasila
  • Ita Rahmawati Fakultas Farmasi, Universitas Pancasila

Abstract

Bamboo Kuning (Bambusa vulgaris Shard) leaves its efficacy as antioxidant, anti-inflammation, antidiabetic and antiulcer. The study aims to know volume edema decrease of rats foot as anti-inflammatory effect and the amount of strectching mice an analgesic effect the decoction of Bamboo Kuning. Anti-inflammatory test used Winter methods. Rats were be diveded into 5 groups: negative control be given aquadest, positive control be given sodium diclofenac 4,367 mg/200g BB, the test groups were given the decoction of  Bamboo Kuning leaves 2,8 mL/200g BB with a concentration of 10%, 20% and 40%. Analgesic testing used methods Sigmund. Mice were divided into 5 groups: negative control be given aquadest, positive control were given sodium diclofenak 0,26 mg/20g BB, the test group was given the boiled of bamboo kuning leaves 0,4 mL/20g BB with concentration 10%, 20% and 40%. Statistic result decoction of leaves Bamboo Kuning dose 2,8 mL/200g BB with concentration 10%, 20% and 40% have anti-inflammatory and analgesic effect. Decoction of Bamboo Kuning leaves dose 2,8 mL/200g BB with concentration of 10%, 20% and 40% have anti-inflammatory and analgesic effect are lower than sodium diclofenac. Increased dose boiled of Bamboo Kuning leaves no provide increased effect as an anti-inflammatory and analgesic.

References

1. Agustina, Ri., D. T. Indrawati, dan M. A. Masruhin. Aktivitas Ekstrak Daun Salam (Eugenia poyantha) Sebagai Antiinflamsi Pada Tikus Putih (Rattus norvegicus). J. Trop. Pharm. Chem. 2015;3(2):120-123.

2. Ernst Mutschler. Dinamika Obat “ Buku ajar Farmakologi dan Toksikologi”. Edisi 5. ITB Bandung; 1991. Hal:177-178

3. Anonim. Masa Depan Obat Tradisional Indonesia Cerah 2008. Diambil dari: https://teknologitinggi.wordpress.com/2008/08/12/masadepan-obat-tradisional-indonesia-cerah/.

4. Narande J. M., Anne W., dan Adithya Y. Uji Efek Antiinflamsi Ekstrak etanol Daun Suji (Dracaena angustifolia Roxb) Terhadap Edema Kaki Tikus Putih Jantan Galur Wistar. Pharmacon. 2013;2(3):14-18.

5. Y. C. Tripathi et al. Evaluation of Total Polyphenol and Antioxidant Activity of Leaves of Bambusa nutans and Bambusa vulgaris. Journal of Pharmacy research 2015: 9 (4), 271-277.

6. NYSreedhar. Synthesis and Characterization of 4-Hydroxy Chalcones Using PEG-400 as a Recyclable Solvent. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2010: 1 (4), 480-48.

7. Sulistian Gan Gunawan, editors, Farmakologi dan Terapi edisi 5 . Jakarta: Departemen Farmakologi dan Terapi: 2007. Hal 231,232

8. B. R. A. Moeryati Soedibyo. Alam Sumber Kesehatan. Balai Pustaka. 1998. Jakarta.

9. Kelompok Kerja Ilmiah Yayasan Pengembangan Obat Bahan Alam Phyto Medika “Pedoman Pengujian dan Pengembangan Fitofarmaka “Penapisan Farmakologi, Pengujian Fitokimia dan Pengujian Klinik”. 1993, hal: 3, 43
Published
2021-10-31
How to Cite
KHAIRANI, Sondang et al. Test Anti-Inflammatory and Analgesic Effect from Decoction of Bamboo Kuning Leaves (Bambusa Vulgaris Schard. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 2, p. 266-271, oct. 2021. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/875>. Date accessed: 22 dec. 2024. doi: https://doi.org/10.35814/jifi.v19i2.875.
Section
Articles