The Effervescent Granule Ethanol Extract of Andaliman Fruits (Zanthoxylum acanthopodium DC.) using Variations of Source Acid and Antioxidant Activity

  • Yunahara Farida Universitas Pancasila
  • Kartiningsih Kartiningsih Universitas Pancasila
  • Febria Hana R Universitas Pancasila

Abstract

Andaliman fruit (Zanthoxylum acanthopodium DC.) contain flavonoids that has antioxidant
activity. This study was conducted to obtain the effervescent granules andaliman fruit extract which has the highest antioxidant activity by DPPH free radical scavenging method. Andaliman fruit was extracted in stages using n-hexane, ethyl acetate and 70% ethanol, then dried using freeze drying method. Furthermore, the dry extract of ethanol is formulated using variation acid sources, namely citric acid and tartaric acid. The results showed that the formulas had moisture rate of 2.30 – 3.95%; fl ow rate of 2.53-4.12 g/sec; the particle size distribution with the fi nes <10%; dissolved time < 2 minutes; and a pH value of 5.48-5.65. The results of the antioxidant activity of formula I-III were 74.0; 84.9 and 91.9 ppm respectively. The conclusion of the research showed that the formula I with a combination of citric acid and tartaric acid is a formula that meets the physical quality requirements and has a strong antioxidant activity with IC50 value of 74.0 ppm.

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Published
2021-04-30
How to Cite
FARIDA, Yunahara; KARTININGSIH, Kartiningsih; R, Febria Hana. The Effervescent Granule Ethanol Extract of Andaliman Fruits (Zanthoxylum acanthopodium DC.) using Variations of Source Acid and Antioxidant Activity. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 1, p. 96-101, apr. 2021. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/883>. Date accessed: 28 sep. 2021. doi: https://doi.org/10.35814/jifi.v19i1.883.
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Articles