The Effervescent Granule Ethanol Extract of Andaliman Fruits (Zanthoxylum acanthopodium DC.) using Variations of Source Acid and Antioxidant Activity

  • Yunahara Farida Universitas Pancasila
  • Kartiningsih Kartiningsih Universitas Pancasila
  • Febria Hana Rahmadani Universitas Pancasila
DOI: https://doi.org/10.35814/jifi.v19i1.883

Abstract

Andaliman fruit (Zanthoxylum acanthopodium DC.) contain flavonoids that has antioxidant
activity. This study was conducted to obtain the effervescent granules andaliman fruit extract which has the highest antioxidant activity by DPPH free radical scavenging method. Andaliman fruit was extracted in stages using n-hexane, ethyl acetate and 70% ethanol, then dried using freeze drying method. Furthermore, the dry extract of ethanol is formulated using variation acid sources, namely citric acid and tartaric acid. The results showed that the formulas had moisture rate of 2.30 – 3.95%; fl ow rate of 2.53-4.12 g/sec; the particle size distribution with the fi nes <10%; dissolved time < 2 minutes; and a pH value of 5.48-5.65. The results of the antioxidant activity of formula I-III were 74.0; 84.9 and 91.9 ppm respectively. The conclusion of the research showed that the formula I with a combination of citric acid and tartaric acid is a formula that meets the physical quality requirements and has a strong antioxidant activity with IC50 value of 74.0 ppm.

References

1. Tensiska, C.Hanny Wijaya, Nuri Andarwulan, Aktivitas antioksidan ekstrak buah andaliman (Zanthoxylum
acanthopodium DC.) dalam beberapa sistem pangan dan kestabilan aktivitasnya terhadap kondisi suhu dan pH. Jurnal Teknologi dan Industri Pangan XIV, 2003(14):25-32.

2. Parhusip, A.J.N. Kajian mekanisme antibakteri ekstrak andaliman (Zanthoxylum acanthopodium DC) terhadap
bakteri patogen [Disertasi]. Sekolah Pascasarjana Institut Pertanian Bogor,2006.

3. Kristanty RE, Suriawati J. The Indonesian Zanthoxylum acanthopodium DC. : Chemical and biological
values. International Journal of Pharmtech Reseach; 2015: 8(6): 313-321.

4. Gultom, S. Flavonoid buah andaliman (Zanthoxylum acanthopodium DC) sebagai inhibitor α-glukosidase.
Bogor: Sekolah Pasca Sarjana Institut Pertanian Bogor, 2011.

5. Widiaswati, B. Aktivitas antioksidan dan imunostimulan ekstrak buah andaliman (Zanthoxylum acanthopodium DC). Bogor: Fakultas Pertanian. Institut pertanian Bogor, 2000.

6. Mohrle, R., Effervescent tablets in pharmaceutical dosage forms tablets, Volume I, 3rd Ed. 1980. h.225-
255, Marcel Dekker Inc., New York.

7. Farnsworth NR. Biological and phytochemical screening of plants. J.of Pharmaceutical Science. 1966. 55 (3), 225-276.

8. Napitupulu FI. Metode pengeringan andaliman (Zanthoxylum acanthopodium DC.) untuk memperoleh mutu
sensori aroma dan sensasi trigeminal yang optimum, 2014.

9. Anam C, Kawiji K, Setiawan RD. Kajian karakteristik fisik dan sensori serta aktivitas antioksidan dari granul
effervescent buah beet (Beta Vulgaris) dengan perbedaan metode granulasi dan kombinasi sumber asam.
Jurnal Teknosains Pangan. 2013 Apr 2;2(2).

10. Fauset,H., Gayser,C., and Dash,AK. Evaluation of quick desintegrating Calcium Carbonate tablets, 2000.

11. Mirantiayu Ningsih. Formulasi tablet effervescent dengan basa kalsium karbonat nano dari herba pegagan
(Centella asiatica (L.) Urban). Jakarta: Fakultas Farmasi Universitas Pancasila; 2010. h.37.
Published
2021-04-30
How to Cite
FARIDA, Yunahara; KARTININGSIH, Kartiningsih; RAHMADANI, Febria Hana. The Effervescent Granule Ethanol Extract of Andaliman Fruits (Zanthoxylum acanthopodium DC.) using Variations of Source Acid and Antioxidant Activity. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 1, p. 96-101, apr. 2021. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/883>. Date accessed: 05 nov. 2024. doi: https://doi.org/10.35814/jifi.v19i1.883.
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Vol 19 No 1 (2021): JIFI
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