The Effect of Anti-Allergic Herbal Formulation on the Quality of Life of Allergic Rhinitis Patients at the Tawangmangu Hortus Medicus Clinic

  • Fajar Novianto Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Zuraida Zulkarnain Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Agus Triyono Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Danang Ardiyanto Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Ulfa Fitriani Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • P. R. Widhi Astana Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Ulfatun Nisa Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional Tawamangu
  • Setyo S. Rahardjo Fakultas Kedokteran Universitas Sebelas Maret

Abstract

Allergies are health problems that can affect a person’s quality of life. It is currently unknown whether the use of anti-allergic herbs can improve the quality of life for allergic patients. The purpose of this study was to determine the effect of giving anti-allergic herbs on the quality of life of patients with allergic rhinitis at the Tawangmangu Hortus Medicus Clinic. The design of this research was a pre-post treatment quasi experimental. A total of 55 subjects were given anti-allergic herbal decoction consisting of sembung, javanese chilies, ginger, and nut grass for 4 weeks and drunk 3 times a day. Before the study and on day 28th, the subjects were examined for quality of life using the Short Form-36. The results were analyzed using the Wilcoxon test. The results showed that there was a significant increase in quality of life between before and after drinking anti-allergic herbal medicine (p<0.05), especially for the dimensions of physical function, energy and general health. The conclusion is that anti-allergic herbs can improve the quality of life for allergic rhinitis patients.

References

1. Ningrum WAC, Hidayati T. Kualitas hidup pasien urolithiasis pada komponen fisik dan komponen mental dengan instrumen short form-36 (SF-36). Jurnal Care. 2016.4(3):70–7.

2. Rachmawati Y, Perwitasari DA. Validasi kuesioner SF-36 versi Indonesia terhadap pasien hipertensi di puskesmas Yogyakarta. Pharmacy. 2014.11(1):14–25.

3. Wistiani W, Notoatmojo H. Hubungan pajanan alergen terhadap kejadian alergi pada anak. SP. 2016.13(3):185.

4. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic rhinitis and its impact on asthma (ARIA) update. Allergy. 2008.63(86):8–160.

5. Leynaert B, Neukirch C, Liard R, Bousquet J, Neukirch
F. Quality of life in allergic rhinitis and asthma: a population-based study of young adults. Am J Respir Crit Care Med. 2000.162(4):1391–6.

6. Widuri A. IgE antibody therapy in alerrgic rhinitis. Mutiara Medika. 2009.9(1):6.

7. Setiap tahun, penderita alergi di Indonesia bertambah 30 persen [serial online]. diambil dari URL: http://www.pdpersi.co.id/content/news. php?mid=5&nid=707&catid=23. diakses 22 Agustus 2020

8. PMK No.003 ttg Saintifikasi jamu dalam penelitian berbasis pelayanan kesehatan.pdf [serial online]. diambil dari URL: http://www.b2p2toot.litbang. kemkes.go.id/temuLAWAK/editor/tinymce/uploaded/ DIP/PMK%20No.003%20ttg%20Saintifikasi%20 Jamu%20Dalam%20Penelitian%20Berbasis%20 Pelayanan%20Kesehatan.pdf. diakses 22 Agustus 2020

9. Triyono A, Ridha P, Ardianto D. Clinical trial the efficacy of boiled hypertension herbs compared with steeped hypertension herbs. Jurnal Ilmu Kefarmasian Indonesia. 2018.16(1):78.

10. Firdawati. Kualitas hidup mahasiswa fakultas kedokteran dengan rinitis alergi dan faktor- faktor yang berpengruh [tesis]. Semarang: UNDIP; 2013.

11. Harsono G, Munasir Z, P Siregar S, Dadi Suyoko H, Kumiati M, Evalina R, et al. Faktor yang diduga menjadi resiko pada anak dengan rinitis alergi di RSU Dr. Cipto Mangunkusumo Jakarta. Jurnal Kedokteran Brawijaya. 2007.23(3):116–20.

12. Su X, Li B, Gu H. Montelukast combined with loratadine can improve the immune function and SF-36 score of patients with allergic rhinitis. Revista Argentina de Clínica Psicológica. 2020.29(3):6.

13. Bunnag C, Leurmarnkul W, Jareoncharsri P, Assanasen P, Pawankar R. Quality of life assessment in Thai patients with allergic rhinoconjunctivitis using the SF- 36 questionnaire (Thai version). Rhinology. 2004.43:6.

14. Aldi Y. Uji efek antialergi dari tumbuhan Andrographis paniculata Nees. dan Blumea balsamifera (L) Dc [tesis]. Bandung: ITB; 2006.

15. Xia Y, Zuo J, Li X, Chen J-W. [Anti-arthritic and anti- oxidative effect of ethyl acetate fraction of Blumea balsamlfera residues in rat adjuvant-induced arthritis]. Zhongguo Zhong Yao Za Zhi. 2014.39(19):3819–23.

16. Winarto EK. Uji efek rebusan buah cabe Jawa (Piper retrofractum Vahl) dosis 175 g/kg BB terhadap kontraksi ileum marmut terisolasi yang diinduksi dengan histamin [tesis]. Surabaya: Ubaya; 2003.

17. Muslichah S. Potensi afrodisiak kandungan aktif buah cabe jawa (Piper Retrofractum Vahl) pada tikus jantan galur Wistar. Jurnal Agroteknologi. 2011.5(2):11.

18. Evizal R. Status Fitofarmaka dan perkembangan agroteknologi cabe jawa (Piper Retrofractum Vahl.). Jurnal Agrotropika. 2013.18(1):34–40.

19. Rahmawati N, Bachri MS. The aphrodisiac effect and toxicity of combination Piper retrofractum L., Centella
asiatica, and Curcuma domestica infusion. Helath Science Journal of Indonesia. 2012.3(1):4.

20. Sunaryo H, Rahmania RA, Dwitiyanti D, Siska S. Aktivitas antioksidan kombinasi ekstrak Jahe Gajah (Zingiber officinale Rosc.) dan zink berdasarkan pengukuran MDA, SOD dan katalase pada mencit hiperkolesterolemia dan hiperglikemia dengan penginduksi streptozotosin. Jurnal Ilmu Kefarmasian Indonesia. 2017.13(2):187–93.

21. Kemenkes RI. Vademenkum tanaman obat untuk saintifikasi jamu jilid 1 dan 2. Jakarta: Balitbangkes; 2010.
Published
2021-04-21
How to Cite
NOVIANTO, Fajar et al. The Effect of Anti-Allergic Herbal Formulation on the Quality of Life of Allergic Rhinitis Patients at the Tawangmangu Hortus Medicus Clinic. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 1, p. 25-29, apr. 2021. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/939>. Date accessed: 28 sep. 2021. doi: https://doi.org/10.35814/jifi.v19i1.939.
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Articles