The Effect of Sambung Nyawa (Gynura procumbens) Leaves Extract to Reduction of Dandruff on The Scalp

  • Neneng Siti Silfi Ambarwati Fakultas Teknik, Universitas Negeri Jakarta
  • Rita Susesty Fakultas Teknik, Universitas Negeri Jakarta
  • Devi Sulastiowati Fakultas Teknik, Universitas Negeri Jakarta


Gynura procumbens is a medicinal plant commonly used in Asian countries such as China, Thailand, Indonesia, Malaysia, and Vietnam. G. procumbens content flavonoids and glycosides and have bacteria activity and anti-fungal activity such as Candida albicans and Aspergillus niger. The purpose of this study was to obtain empirical data about the effect of using the G. procumbens leaves extract on reducing dandruff on the scalp. The extract was obtained by the maceration method using 70% ethanol solvent. The phytochemical compound content is determined with spectrophotometry ultraviolet. Two observers observe the scalp by using observation sheets and grating instruments assisted by a skin and hair analyzer. The reduction of scalp dandruff was the difference between the initial the results and the final test (after treatment). The sample was selected using a purposive sampling technique totaling ten people and divided into two groups (experimental and control groups). The results showed that the calculation of hypothesis testing after analyzing the data obtained a value of t count (5.817)>t table (1.86). This showed an effect of using the G. procumbens leaves extract as a shampoo for reducing dandruff on the scalp. The use of G. procumbens leaves extract as shampoo can reduce dandruff.


1. Borda LJ, Wikramanayake TC. Seborrheic dermatitis and dandruff: A Comprehensive Review. J Clin Investig Dermatol. 2016;3(2).

2. Tan H, Chan K, Pusparajah P, Lee L, Goh B, Lee L. Gynura procumbens: an overview of the biological activities. Front Pharmacol. 2016;7(52):1–14.

3. Mou KM, Dash PR. A comprehensive review on Gynura procumbens leaves. Int J Pharmacogn. 2016;3(4):167–74.

4. Ambarwati A, Sujono TA, Sintowati R. Uji aktivitas ekstrak daun pandan wangi (Pandanus amaryllifolius
Jurnal Ilmu Kefarmasian Indonesia Roxb.) sebagai antibakteri. In: The 3rd University Research Colloqium 2016. 2016. p. 222–8.

5. Winarti W, Djamil R, Zaidan S, Raymond. In- vitro a-glucosidase inhibition activities test from standardized sambung nyawa (Gynura procumbens (Lour.) Merr.) leaves extract. In: International Seminar Pokjanas TOI Faculty of Pharmacy Pancasila University. 2016. p. 90–3.

6. Rajesh BR, Potty VP, Sreelekshmy SG. Study of total phenol, flavonoids, tannin contents and phytochemical screening of various crude extracts of Terminalia catappa leaf , stem bark and fruit. Int J Appl Pure Sci Agric. 2016;02(06):291–6.

7. Taherdoost H. Sampling methods in research methodology: how to choose a sampling technique for research. Int J Acad Res Manag [Internet]. 2016;5(2):18–27. Available from: https://www.ssrn. com/abstract=3205035

8. Etikan I, Musa SA, Alkassim RS. Comparison of convenience sampling and purposive sampling. Am J Theor Appl Stat. 2016;5(1):1–4.

9. Flannelly LT, Flannelly KJ, Jankowski KRB. Independent, dependent, and other variables in healthcare and chaplaincy Research. J Health Care Chaplain. 2014;20(4):161–70.

10. Rochon J, Gondan M, Kieser M. To test or not to test: preliminary assessment of normality when comparing two independent samples. BMC Med Res Methodol. 2012;12(81):1–11.

11. Sudjana. Metode statistika. Bandung: Penerbit Tarsito; 2009. 468 p.

12. Arikunto S. Prosedur penelitian suatu pendekatan praktik. Jakarta: Rineka Cipta; 2006. 195 p.

13. Sugiyono. Statistika untuk penelitian. Bandung: PT Alfa Beta; 2013. 181 p.

14. Dewatisari WF, Rumiyanti L, Rakhmawati I. Rendemen dan skrining fitokimia pada ekstrak daun Sanseviera sp. J Penelit Pertan Terap. 2018;17(3):197.

15. Derakhshan Z, Ferrante M, Tadi M, Ansari F, Heydari A, Hosseini MS, et al. Antioxidant activity and total phenolic content of ethanolic extract of pomegranate peels, juice and seeds. Food Chem Toxicol. 2018;114:108–11.

16. Djapiala FY, Montolalu LADY, Mentang F. Kandungan total fenol dalam rumput laut Caulerpa racemosa yang berpotensi sebagai antioksidan. Media Teknol Has Perikan. 2013;1(2):12–30.

17. Gianeti MD, Mercurio DG, Campos PMBGM. The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient. Dermatol Ther. 2013;26:267–71.

18. Kumar RSAS, Bharathi RA, Lakshmipriya R, Devi CS, Sivaranjani A, Banumathi T. Formulation of antimalassezic shampoo from datura metel and prosopis juliflora. Indo Am J Pharm Res. 2017;7(11):905–8.

19. Patel I, Talathi A. Use of traditional indian herbs for the formulation of shampoo and their comparative analysis. Int J Pharm Pharm Sci. 2016;8(3):28–32.

20. P EA, Harindran J. Pharmacognostic evaluation and formulation of shampoo using Sarcostigma kleinii wight & ARN leaves Fam : Icacinaceae. Pharma Innov J. 2019;8(11):220–3.

21. Raju KS. Comparison of antifungal activity of plant extracts and shampoos against dandruff causing organism Malassezia species. Int J Adv Res Ideas Innov Technol ISSN. 2019;5(3):1008–13.

22. Y YK. Pengaruh pemanfaatan shampo ekstrak gambir terhadap perawatan kulit kepala berketombe. E-Journal Home Econ Tour. 2017;14(1):1–23.
How to Cite
AMBARWATI, Neneng Siti Silfi; SUSESTY, Rita; SULASTIOWATI, Devi. The Effect of Sambung Nyawa (Gynura procumbens) Leaves Extract to Reduction of Dandruff on The Scalp. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 19, n. 1, p. 49-55, apr. 2021. ISSN 2614-6495. Available at: <>. Date accessed: 20 june 2021. doi: