Physical Stability Test and Determination of Total Flavonoid Content of Watermelon (Citrullus lanatus) Fruit Mesocarp Extract Gel Preparation

  • Indri Kusuma Dewi PUI Pujakesuma Poltekkes Kemenkes Surakarta
  • Nur Atikah Department of Pharmacy, Poltekkes Kemenkes Surakarta,
  • Nabila Putri Department of Pharmacy, Poltekkes Kemenkes Surakarta,

Abstract

The content of flavonoids in the white skin or mesocarp of watermelon has antioxidant power so that the active substance can be used in the manufacture of cosmetics, one of which is a gel dosage form. This type of research is observational with a descriptive research design. The purpose of this study was to obtain data on the stability of the watermelon (Citrullus lanatus) mesocarp extract gel preparation using the cycling test method. Physical stability evaluations were carried out, including organoleptic, homogeneity, pH, adhesion, spreadability, and viscosity. The results showed that the organoleptic observation of the preparation was in the form of a semi-solid, had a characteristic aromatic odor of the extract, and had a brownish-yellow color. As for the test results for the entire homogeneous cycle, the average pH range is 4.75 - 5, adhesion is 2.45 - 3.96 seconds, dispersion is 5.59 - 6.67 cm, and viscosity is 5426 - 6830 cps, and total flavonoid content of the gel preparation was 5.27%. This study concluded that the gel preparation was physically stable before and after 12 days of storage and contained 5.27% flavonoids.

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Published
2022-10-31
How to Cite
DEWI, Indri Kusuma; ATIKAH, Nur; PUTRI, Nabila. Physical Stability Test and Determination of Total Flavonoid Content of Watermelon (Citrullus lanatus) Fruit Mesocarp Extract Gel Preparation. JURNAL ILMU KEFARMASIAN INDONESIA, [S.l.], v. 20, n. 2, p. 264-271, oct. 2022. ISSN 2614-6495. Available at: <http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/1319>. Date accessed: 08 feb. 2023. doi: https://doi.org/10.35814/jifi.v20i2.1319.
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Articles